Gene Symbol | SRP68 |
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Entrez Gene | 6730 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | signal recognition particle 68kDa |
Other Description | signal recognition particle 68 kDa protein|signal recognition particle 68kD|signal recognition particle subunit SRP68 |
Swissprots | Q9UHB9 B3KWY7 Q8NCJ4 B3KUU5 Q8WUK2 G3V1U4 |
Accessions | CAF86767 EAW89358 EAW89359 EAW89360 EAW89361 EAW89362 EAW89363 Q9UHB9 AF195951 AAF24308 AK002002 BAG51001 AK027320 BAB55040 AK027322 BAB55041 AK074698 BAC11145 AK092935 AK097962 BAG53557 AK098159 AK126258 BAG54299 AK301100 BAG62699 AL512708 AU137443 BC000760 BC013308 BC020238 AAH20238 DB315535 DQ786315 NM_001260502 NP_001247431 NM_001260503 NP_001247432 NM_014230 NP_055045 NR_048541 |
Function | Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. |
Subcellular Location | Cytoplasm. Nucleus, nucleolus. |
Top Pathways | Protein export |
SRP68 CRISPR/Cas9 KO Plasmid (h) - sc-404378 from Santa Cruz Biotechnology
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SRP68 HDR Plasmid (h) - sc-404378-HDR from Santa Cruz Biotechnology
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SRP68 Double Nickase Plasmid (h) - sc-404378-NIC from Santa Cruz Biotechnology
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SRP68 Double Nickase Plasmid (h2) - sc-404378-NIC-2 from Santa Cruz Biotechnology
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SRP68 CRISPR Activation Plasmid (h) - sc-404378-ACT from Santa Cruz Biotechnology
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SRP68 CRISPR Activation Plasmid (h2) - sc-404378-ACT-2 from Santa Cruz Biotechnology
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SRP68 Lentiviral Activation Particles (h) - sc-404378-LAC from Santa Cruz Biotechnology
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SRP68 Lentiviral Activation Particles (h2) - sc-404378-LAC-2 from Santa Cruz Biotechnology
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SRP68 siRNA (h) - sc-94109 from Santa Cruz Biotechnology
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SRP68 shRNA Plasmid (h) - sc-94109-SH from Santa Cruz Biotechnology
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SRP68 shRNA (h) Lentiviral Particles - sc-94109-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU113121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20581 from Sigma-Aldrich
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SRP68 siRNA (Human) - CRH4597 from Cohesion Biosciences
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SRP68 - MBS8220069 from MyBioSource
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Human SRP68 siRNA - orb265099 from Biorbyt
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SRP68 shRNA Plasmid (Human) - CHH4597 from Cohesion Biosciences
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SRP68 miRNA 3'UTR clone - MiUTR3H-07143 from Creative biogene
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