| Gene Symbol |
TRIP11
|
| Entrez Gene |
9321
|
| Alt Symbol |
ACG1A, CEV14, GMAP-210, TRIP-11, TRIP230
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thyroid hormone receptor interactor 11
|
| Other Description |
Golgi-microtubule-associated protein of 210 kDa|TR-interacting protein 11|clonal evolution-related gene on chromosome 14 protein|golgi-associated microtubule-binding protein 210|thyroid receptor-interacting protein 11
|
| Swissprots |
B2RUT2 O14689 O95949 Q15643 O15154
|
| Accessions |
EAW81468 EAW81469 Q15643 AF007217 AAD09135 AF011368 AAB84386 AK307489 AL599917 AW002857 BC002656 BC069008 BC146845 AAI46846 BM770594 BU628691 BX113728 BX486357 BX641024 CAE46015 DA111770 L40380 AAC41730 Y12490 CAA73095 XM_005268214 XP_005268271 XM_005268215 XP_005268272 XM_006720321 XP_006720384 XM_011537361 XP_011535663 XR_943560 NM_004239 NP_004230
|
| Function |
Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB- modulated transcription. Golgi auto-antigen; probably involved in maintaining cis-Golgi structure. {ECO:0000269|PubMed:10189370, ECO:0000269|PubMed:9256431}.
|
| Subcellular Location |
Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:10189370}; Peripheral membrane protein {ECO:0000269|PubMed:10189370}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10189370}. Note=Associates with the ends of centrosome-nucleated microtubules.
|
| Tissue Specificity |
Highly expressed in pancreas, muscle, heart, testis, peripheral blood leukocytes, and in several leukemia cell lines. Detected at intermediate levels in placenta and kidney, and at low levels in brain and lung. {ECO:0000269|PubMed:10189370, ECO:0000269|PubMed:9373237}.
|