| Gene Symbol |
PARD3B
|
| Entrez Gene |
117583
|
| Alt Symbol |
ALS2CR19, PAR3B, PAR3L, PAR3beta
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
par-3 family cell polarity regulator beta
|
| Other Description |
PAR3-L protein|amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 19|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein|par-3 partitioning defective 3 homolog B|partitioning defective 3 homolog B|partitioning defective 3-like protein|partitioning-defective 3-beta
|
| Swissprots |
Q96NX6 Q96N09 Q8IUC9 E9PE87 Q8IUC7 Q8TEW8 Q96DK9 Q96Q29 Q96NX7
|
| Accessions |
AAX76515 AAX88974 AAX93083 AAY14757 AAY15023 AAY24228 AAY24245 AAY24325 EAW70358 EAW70359 EAW70360 Q8TEW8 AB053321 BAB69028 AB073472 BAC54035 AB092439 BAC54285 AF428250 AAL30664 AF428251 AAL30665 AF466152 AAL79827 AI742400 AK056157 BAB71106 AK057965 BAB71623 AK312083 BAG35019 AL832951 AW274720 BC012984 BC156252 AAI56253 BC172499 AAI72499 BF434006 XM_011510550 XP_011508852 XM_011510551 XP_011508853 XM_011510552 XP_011508854 XM_011510553 XP_011508855 NM_001302769 NP_001289698 NM_057177 NP_476518 NM_152526 NP_689739 NM_205863 NP_995585
|
| Function |
Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions.
|
| Subcellular Location |
Endomembrane system. Cell junction. Cell junction, tight junction. Note=Partially localized along the cell- cell contact region. Colocalizes with TJP1 to epithelial tight junctions.
|
| Tissue Specificity |
Highly expressed in kidney, lung and skeletal muscle. Expressed at intermediate levels in brain, heart, placenta, liver and pancreas. Isoform 1 is predominant, while isoform 2 and isoform 3 are expressed at lower levels.
|