| Gene Symbol |
WBSCR17
|
| Entrez Gene |
64409
|
| Alt Symbol |
GALNACT17, GALNT16, GALNT20, GALNTL3, GalNAc-T5L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Williams-Beuren syndrome chromosome region 17
|
| Other Description |
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like 3|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16|galNAc-T-like protein 3|polypeptide GalNAc transferase 3|polypeptide GalNAc transferase-like protein 3|polypeptide N-acetylgalactosaminyltransferase WBSCR17|polypeptide N-acetylgalactosaminyltransferase-like 3|pp-GaNTase-like protein 3|pp-GalNAc-transferase 20|protein-UDP acetylgalactosaminyltransferase-like protein 3|putative polypeptide N-acetylgalactosaminyltransferase-like protein 3|williams-Beuren syndrome chromosomal region 17 protein
|
| Swissprots |
Q6IS24 Q9NTA8 Q8NFV9
|
| Accessions |
EAL23969 EAX07897 EAX07898 EAX07899 EAX07900 Q6IS24 AB078148 BAD93180 AF410457 AAM62306 AJ626726 CAF25037 AK022143 AK091379 BAG52344 AK094958 BAG52964 AK126044 BAG54282 AK290036 BAF82725 AL137431 CAB70734 BC067524 AAH67524 BC067525 AAH67525 BC069624 AAH69624 BC069628 AAH69628 BC069636 AAH69636 BC069645 AAH69645 BC069997 AAH69997 BE669980 CR749675 CAH18466 XM_011516467 XP_011514769 XM_011516468 XP_011514770 XM_011516469 XP_011514771 NM_022479 NP_071924
|
| Function |
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. {ECO:0000250}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in brain and heart. Weakly expressed in kidney, liver, lung and spleen. {ECO:0000269|PubMed:12073013}.
|
| Top Pathways |
Mucin type O-Glycan biosynthesis
|