Gene Symbol | Mthfr |
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Entrez Gene | 17769 |
Alt Symbol | AI323986 |
Species | Mouse |
Gene Type | protein-coding |
Description | 5,10-methylenetetrahydrofolate reductase |
Other Description | methylenetetrahydrofolate reductase |
Swissprots | Q8CDE4 Q9WU20 |
Accessions | AAD20313 AAL17641 AAL17642 AAN40867 AAN40868 EDL14794 EDL14795 EDL14796 EDL14797 EDL14798 Q9WU20 AF404270 AAN40872 AF404271 AAN40873 AF404272 AAN40874 AF404273 AAN40875 AF404274 AAN40876 AK030192 BAC26832 AK043144 BAE43318 AK149795 AK150159 BAE29349 AK191706 AK199913 AK219632 BB726553 BC019719 BC051017 AAH51017 BC052466 AAH52466 BC100550 AAI00551 XM_006535928 XP_006535991 XM_006535929 XP_006535992 XM_006535930 XP_006535993 XM_006535931 XP_006535994 XM_006535932 XP_006535995 XM_006535933 XP_006535996 XM_006538617 XP_006538680 XM_006538618 XP_006538681 XM_006538619 XP_006538682 XM_006538620 XP_006538683 XM_006538621 XP_006538684 XM_006538622 XP_006538685 XR_389856 XR_389857 XR_390731 XR_390732 XR_390733 XR_882363 NM_001161798 NP_001155270 NM_010840 NP_034970 NR_027809 |
Function | Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine. |
Top Pathways | Carbon metabolism, One carbon pool by folate |
MTHFR CRISPR/Cas9 KO Plasmid (m) - sc-421741 from Santa Cruz Biotechnology
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MTHFR HDR Plasmid (m) - sc-421741-HDR from Santa Cruz Biotechnology
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MTHFR Double Nickase Plasmid (m) - sc-421741-NIC from Santa Cruz Biotechnology
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MTHFR Double Nickase Plasmid (m2) - sc-421741-NIC-2 from Santa Cruz Biotechnology
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MTHFR CRISPR Activation Plasmid (m) - sc-421741-ACT from Santa Cruz Biotechnology
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MTHFR CRISPR Activation Plasmid (m2) - sc-421741-ACT-2 from Santa Cruz Biotechnology
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MTHFR Lentiviral Activation Particles (m) - sc-421741-LAC from Santa Cruz Biotechnology
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MTHFR Lentiviral Activation Particles (m2) - sc-421741-LAC-2 from Santa Cruz Biotechnology
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MTHFR siRNA (m) - sc-149681 from Santa Cruz Biotechnology
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MTHFR shRNA Plasmid (m) - sc-149681-SH from Santa Cruz Biotechnology
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MTHFR shRNA (m) Lentiviral Particles - sc-149681-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU050321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN35943 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35943 from Sigma-Aldrich
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MTHFR siRNA (Mouse) - CRM2640 from Cohesion Biosciences
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shRNA set against Mouse MTHFR (NM_010840.3) - SHH346356 from Creative biogene
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shRNA set against Mouse Mthfr(NM_001161798.1) - SHH206237 from Creative biogene
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Mouse MTHFR siRNA - orb282116 from Biorbyt
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MTHFR shRNA Plasmid (Mouse) - CHM2640 from Cohesion Biosciences
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MTHFR miRNA 3'UTR clone - MiUTR1M-07370 from Creative biogene
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