Gene Symbol | STK38 |
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Entrez Gene | 11329 |
Alt Symbol | NDR, NDR1 |
Species | Human |
Gene Type | protein-coding |
Description | serine/threonine kinase 38 |
Other Description | NDR1 protein kinase|Ndr Ser/Thr kinase-like protein|nuclear Dbf2-related kinase 1|serine/threonine-protein kinase 38 |
Swissprots | Q503A1 Q15208 |
Accessions | CAG44584 EAX03894 EAX03895 EAX03896 Q15208 AF034187 AAD50529 AF034188 AAD50530 AK095337 AK312559 BAG35456 BC012085 AAH12085 BC095413 AAH95413 CB852856 DA459946 EU832099 ACE87449 EU832192 ACE86762 Z35102 CAA84485 XM_005248839 XP_005248896 XM_006714988 XP_006715051 XM_006714989 XP_006715052 XM_011514277 XP_011512579 XM_011514278 XP_011512580 XR_926047 NM_001305102 NP_001292031 NM_007271 NP_009202 |
Function | Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2. {ECO:0000269|PubMed:12493777, ECO:0000269|PubMed:15197186, ECO:0000269|PubMed:17906693, ECO:0000269|PubMed:7761441}. |
Subcellular Location | Nucleus. Cytoplasm. |
Tissue Specificity | Ubiquitously expressed with highest levels observed in peripheral blood leukocytes. {ECO:0000269|PubMed:15197186, ECO:0000269|PubMed:7761441}. |
NDR1 CRISPR/Cas9 KO Plasmid (h) - sc-402716 from Santa Cruz Biotechnology
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NDR1 HDR Plasmid (h) - sc-402716-HDR from Santa Cruz Biotechnology
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NDR1 Double Nickase Plasmid (h) - sc-402716-NIC from Santa Cruz Biotechnology
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NDR1 Double Nickase Plasmid (h2) - sc-402716-NIC-2 from Santa Cruz Biotechnology
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NDR1 CRISPR Activation Plasmid (h) - sc-402716-ACT from Santa Cruz Biotechnology
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NDR1 CRISPR Activation Plasmid (h2) - sc-402716-ACT-2 from Santa Cruz Biotechnology
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NDR1 Lentiviral Activation Particles (h) - sc-402716-LAC from Santa Cruz Biotechnology
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NDR1 Lentiviral Activation Particles (h2) - sc-402716-LAC-2 from Santa Cruz Biotechnology
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NDR1 siRNA (h) - sc-44366 from Santa Cruz Biotechnology
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NDR1 shRNA Plasmid (h) - sc-44366-SH from Santa Cruz Biotechnology
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NDR1 shRNA (h) Lentiviral Particles - sc-44366-V from Santa Cruz Biotechnology
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STK38 RNAi - H00011329-R01V from Novus Biologicals
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MISSION® esiRNA - EHU119371 from Sigma-Aldrich
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MISSION® siRNA - SIHK2190 from Sigma-Aldrich
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MISSION® siRNA - SIHK2189 from Sigma-Aldrich
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MISSION® siRNA - SIHK2191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20743 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20743 from Sigma-Aldrich
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STK38 siRNA (Human) - CRH7756 from Cohesion Biosciences
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STK38 RNAi - H00011329-R03 from Novus Biologicals
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STK38 - MBS8216327 from MyBioSource
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shRNA set against Human STK38 (NM_007271.2) - SHH419876 from Creative biogene
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shRNA set against Human STK38(NM_007271.2) - SHR004146 from Creative biogene
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Human STK38 siRNA - orb268258 from Biorbyt
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STK38 shRNA Plasmid (Human) - CHH7756 from Cohesion Biosciences
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