Gene Symbol | GALNT14 |
---|---|
Entrez Gene | 79623 |
Alt Symbol | GALNT15, GalNac-T10, GalNac-T14 |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase 14 |
Other Description | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T10|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T14|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)|polypeptide GalNAc transferase 14|polypeptide N-acetylgalactosaminyltransferase 15|pp-GaNTase 14|protein-UDP acetylgalactosaminyltransferase 14 |
Swissprots | Q96FL9 Q53SU1 Q9H827 Q4ZG75 Q8IVI4 Q53TJ0 B3KV89 Q9BRH1 Q9H9J8 |
Accessions | AAX88899 AAX93209 AAY24301 CBX51403 EAX00486 EAX00487 EAX00488 EAX00489 Q96FL9 AB078144 BAC56889 AJ505966 CAD44543 AK022753 BAB14227 AK074394 AK091313 BAC03634 AK122747 BAG53701 AK225808 AK298735 BAH12861 AK309417 AL713663 AY358758 AAQ89118 BC006269 AAH06269 BC010659 AAH10659 DA752701 JF432232 ADZ15449 Y09324 CAA70505 XM_011533104 XP_011531406 XM_011533105 XP_011531407 XM_011533106 XP_011531408 NM_001253826 NP_001240755 NM_001253827 NP_001240756 NM_024572 NP_078848 NR_045602 |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Detected in renal tubules (at protein level). Highly expressed in fetal and adult kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bladder, uterus, placenta, testis, ovary, skeletal muscle, leukocyte, B-cell, bone marrow, fetal brain, fetal thymus, fetal lung, fetal liver, fetal small intestine, fetal spleen, fetal skeletal and fetus. Detected in renal tubules (at protein level). {ECO:0000269|PubMed:12507512, ECO:0000269|PubMed:20179215}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
Human GALNT14 full length protein - ab164052 from Abcam
|
||||||||||
Human GALNT14 protein fragment - ab164053 from Abcam
|
||||||||||
GALNT14 Antibody Blocking Peptide - LS-E6045 from LifeSpan Bioscience
|
||||||||||
GALNT14 Antibody Blocking Peptide - LS-E17997 from LifeSpan Bioscience
|
||||||||||
Recombinant Human GALNT14 Protein - H00079623-Q01 from Novus Biologicals
|
||||||||||
GALNT14 Recombinant Protein - H00079623-P01 from Novus Biologicals
|
||||||||||
GALNT14-Antibody-N-term-Blocking-Peptide - BP18637a from Abgent, a WuXi AppTec company
|
||||||||||
Human GALNT14 protein - orb246599 from Biorbyt
|
||||||||||
Human GalNAc-T10 (His Tag) protein - orb179597 from Biorbyt
|
||||||||||
GALNT14 Blocking Peptide - 33R-4908 from Fitzgerald
|
||||||||||
GALNT14 - H00079623-P01-10 from Acris Antibodies
|
||||||||||
GALNT14 - H00079623-P01-25 from Acris Antibodies
|
||||||||||
GALNT14 - H00079623-Q01-10 from Acris Antibodies
|
||||||||||
GALNT14 - H00079623-Q01-25 from Acris Antibodies
|
||||||||||
GALNT14 fusion protein - ag10344 from Proteintech Group
|
||||||||||
GALNT14 fusion protein - Ag10470 from Proteintech Group
|
||||||||||
Recombinant human Polypeptide N-acetylgalactosaminyltransferase 14 - CSB-EP836212HU CSB-BP836212HU CSB-MP836212HU from Cusabio
|
||||||||||
Recombinant human Polypeptide N-acetylgalactosaminyltransferase 14 - CSB-EP836212HU from Cusabio
|
||||||||||
Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 14(GALNT14) - CSB-YP836212HU CSB-BP836212HU CSB-MP836212HU from Cusabio
|
||||||||||
Polypeptide N-acetylgalactosaminyltransferase 14, Recombinant Protein - MBS1429647 from MyBioSource
|
||||||||||
Recombinant Human GALNT14 Protein, CF - 9077-GT from R&D Systems
|
||||||||||
GALNT14 Peptide, Human - M34GP06079H from Creative Peptides
|
||||||||||
GALNT14 Recombinant Protein (OPCA02371) - OPCA02371 from Aviva Systems Biology
|
||||||||||
Recombinant human Polypeptide N-acetylgalactosaminyltransferase 14 - AP71416 from Signalway Antibody
|
||||||||||
GALNT14 Recombinant Protein Antigen - NBP2-56187PEP from Novus Biologicals
|