NR1I3

Gene Symbol	NR1I3
Entrez Gene	9970
Alt Symbol	CAR, CAR1, MB67
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 1, group I, member 3
Other Description	constitutive activator of retinoid response|constitutive active receptor|constitutive active response|constitutive androstane nuclear receptor variant 2|constitutive androstane nuclear receptor variant 3|constitutive androstane nuclear receptor variant 4|constitutive androstane nuclear receptor variant 5|constitutive androstane receptor|nuclear receptor subfamily 1 group I member 3|orphan nuclear hormone receptor|orphan nuclear receptor MB67
Swissprots	Q6GZ79 E9PC13 E9PHC8 Q6GZ83 Q5VTW6 Q6GZ89 F1D8Q1 Q5VTW5 E9PH10 Q6GZ76 Q6GZ82 E9PGH6 E9PDU3 Q6GZ87 E9PHN4 Q0VAC9 Q6GZ84 Q14994 Q6GZ68 F1D8Q0 E9PB75 Q6GZ78 Q6GZ85 Q4U0F0 Q6GZ77
Accessions	EAW52608 EAW52609 EAW52610 Q14994 AA918394 AB307702 BAH02293 AK303757 BAH14039 AK303796 BAH14053 AK310773 AK316208 BAH14579 AY572806 AAT47159 AY572807 AAT47160 AY572808 AAT47161 AY572809 AAT47162 AY572810 AAT47163 AY572811 AAT47164 AY572812 AAT47165 AY572813 AAT47166 AY572814 AAT47167 AY572815 AAT47168 AY572816 AAT47169 AY572817 AAT47170 AY572818 AAT47171 AY572819 AAT47172 AY572820 AAT47173 AY572821 AAT47174 AY572822 AAT47175 AY572823 AAT47176 AY572824 AAT47177 AY572825 AAT47178 AY572826 AAT47179 AY572827 AAT47180 BC030972 BC069626 AAH69626 BC069651 AAH69651 BC121120 AAI21121 BC121121 AAI21122 CB124867 DQ022681 AAY56401 HQ447449 ADQ31935 HQ692838 ADZ17349 HQ692839 ADZ17350 HQ692840 ADZ17351 HQ692841 ADZ17352 HQ709178 ADZ17385 XM_005245693 XP_005245750 XM_005245694 XP_005245751 XM_005245697 XP_005245754 XM_011510237 XP_011508539 NM_001077469 NP_001070937 NM_001077470 NP_001070938 NM_001077471 NP_001070939 NM_001077472 NP_001070940 NM_001077473 NP_001070941 NM_001077474 NP_001070942 NM_001077475 NP_001070943 NM_001077476 NP_001070944 NM_001077477 NP_001070945 NM_001077478 NP_001070946 NM_001077479 NP_001070947 NM_001077480 NP_001070948 NM_001077481 NP_001070949 NM_001077482 NP_001070950 NM_005122 NP_005113
Function	Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Subcellular Location	Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7. {ECO:0000250}.
Tissue Specificity	Predominantly expressed in liver.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Constitutive androstane receptor full length protein - ab83193 from Abcam Category Protein Source E. coli Species Human

Human Constitutive androstane receptor protein fragment - ab82072 from Abcam Category Protein Source E. coli Species Human

Human Constitutive androstane receptor protein fragment - ab81846 from Abcam Category Protein Source E. coli Species Human

NR1I3 / CAR Antibody Blocking Peptide - LS-E3411 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR1I3 / CAR Antibody Blocking Peptide - LS-E16655 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR1I3 / CAR Antibody Blocking Peptide - LS-E13591 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR1I3 / CAR Antibody Blocking Peptide - LS-E13285 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CAR/NR1I3 Protein - H00009970-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human CAR/NR1I3 Protein - H00009970-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NR1I3-Antibody-Center-Blocking-Peptide - BP14587c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NR1I3 Blocking Peptide - 33R-5759 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NR1I3 Blocking Peptide - 33R-7407 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NR1I3 - H00009970-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

NR1I3 - H00009970-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NR1I3 - H00009970-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NR1I3 fusion protein - ag15378 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human NR1I3, His-tagged - NR1I3-26254TH from Creative Biomart Category Protein Source E. coli

Recombinant Human NR1I3 - NR1I3-26255TH from Creative Biomart Category Protein Source E. coli

Recombinant Human NR1I3 - NR1I3-26256TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Constitutive androstane receptor Hsp90 complex, GST-tagged - NR1I3-108H from Creative Biomart Category Protein Source Sf9 insect cells Species Human

Recombinant Human Nuclear Receptor Subfamily 1, Group I, Member 3 - NR1I3-1020H from Creative Biomart Category Protein Source E. coli.

Recombinant Human NR1I3, Ligand Binding Domain - NR1I3-1021H from Creative Biomart Category Protein Source E.coli.

Recombinant Human NR1I3, Ligand Binding Domain, GST-tagged - NR1I3-1022H from Creative Biomart Category Protein Source E.coli.

Recombinant Human Nuclear Receptor Subfamily 1, Group I, Member 3, GST-tagged - NR1I3-1277H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Nuclear Receptor Subfamily 1, Group I, Member 3 - NR1I3-1278H from Creative Biomart Category Protein Source E. coli Species Human

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