| Gene Symbol | GABRR3 |
|---|---|
| Entrez Gene | 200959 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) |
| Other Description | GABA(A) receptor subunit rho-3|GABA(C) receptor|gamma-aminobutyric acid receptor subunit rho-3 |
| Swissprots | A8MPY1 Q9UIV9 |
| Accessions | A8MPY1 CAB60835 CR749263 NM_001105580 NP_001099050 NR_047685 |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. {ECO:0000250}. |
| Subcellular Location | Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
MISSION® esiRNA - EHU229451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9060 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9060 from Sigma-Aldrich
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GABRR3 siRNA (Human) - CRJ6273 from Cohesion Biosciences
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GABRR3 - MBS828233 from MyBioSource
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shRNA set against Human GABRR3 (NM_001105580.2) - SHH298653 from Creative biogene
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Human GABRR3 siRNA - orb276774 from Biorbyt
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GABRR3 shRNA Plasmid (Human) - CHJ6273 from Cohesion Biosciences
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