Gene Symbol | SLC34A2 |
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Entrez Gene | 10568 |
Alt Symbol | NAPI-3B, NAPI-IIb, NPTIIb |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
Other Description | sodium-dependent phosphate transport protein 2B|sodium/phosphate cotransporter 2B|solute carrier family 34 (sodium phosphate), member 2|type II sodium-dependent phosphate transporter 3b |
Swissprots | Q9P0V7 Q8WYA9 Q8N2K2 A5PL17 O95436 |
Accessions | EAW92842 O95436 AF111856 AAC98695 AF146796 AAF31328 AK075015 BAC11354 AK075045 AK075046 AK292675 BAF85364 AK314514 BC142704 AAI42705 BC146666 AAI46667 CA435368 CN479082 DB201517 DB241180 KM822236 AJE59606 NM_001177998 NP_001171469 NM_001177999 NP_001171470 NM_006424 NP_006415 |
Function | May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium. {ECO:0000269|PubMed:10329428, ECO:0000269|PubMed:10610722}. |
Top Pathways | Mineral absorption |
NPT2b CRISPR/Cas9 KO Plasmid (h) - sc-403580 from Santa Cruz Biotechnology
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NPT2b HDR Plasmid (h) - sc-403580-HDR from Santa Cruz Biotechnology
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NPT2b Double Nickase Plasmid (h) - sc-403580-NIC from Santa Cruz Biotechnology
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NPT2b Double Nickase Plasmid (h2) - sc-403580-NIC-2 from Santa Cruz Biotechnology
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NPT2b CRISPR Activation Plasmid (h) - sc-403580-ACT from Santa Cruz Biotechnology
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NPT2b CRISPR Activation Plasmid (h2) - sc-403580-ACT-2 from Santa Cruz Biotechnology
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NPT2b Lentiviral Activation Particles (h) - sc-403580-LAC from Santa Cruz Biotechnology
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NPT2b Lentiviral Activation Particles (h2) - sc-403580-LAC-2 from Santa Cruz Biotechnology
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NPT2b siRNA (h) - sc-89266 from Santa Cruz Biotechnology
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NPT2b shRNA Plasmid (h) - sc-89266-SH from Santa Cruz Biotechnology
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NPT2b shRNA (h) Lentiviral Particles - sc-89266-V from Santa Cruz Biotechnology
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SLC34A2 RNAi - H00010568-R01 from Novus Biologicals
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MISSION® esiRNA - EHU121661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19570 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19570 from Sigma-Aldrich
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SLC34A2 siRNA (Human) - CRH7189 from Cohesion Biosciences
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SLC34A2 - MBS8232476 from MyBioSource
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shRNA set against Human SLC34A2 (NM_006424.2) - SHH410532 from Creative biogene
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shRNA set against Human SLC34A2(NM_006424.2) - SHL006780 from Creative biogene
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SLC34A2 shRNA Plasmid (Human) - CHH7189 from Cohesion Biosciences
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SLC34A2 miRNA 3'UTR clone - MiUTR1H-09532 from Creative biogene
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