Gene Symbol | PIGP |
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Entrez Gene | 51227 |
Alt Symbol | DCRC, DCRC-S, DSCR5, DSRC |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class P |
Other Description | Down syndrome critical region gene 5|Down syndrome critical region protein 5|Down syndrome critical region protein C|PIG-P|phosphatidylinositol N-acetylglucosaminyltransferase subunit P|phosphatidylinositol glycan, class P|phosphatidylinositol-glycan biosynthesis class P protein|phosphatidylinositol-n-acetylglucosaminyltranferase subunit |
Swissprots | Q53Y28 Q96KI1 B2RB18 J3KR75 B2RE99 D3DSG7 P57054 Q9NZA6 B5BU92 |
Accessions | BAA95512 CAE93962 EAX09724 EAX09725 EAX09726 EAX09727 EAX09728 P57054 AB035742 BAA95633 AB035743 BAA95634 AB035744 BAA95635 AB035745 BAA95636 AB037162 BAA96871 AB037163 BAA96872 AB037164 BAA96873 AB039659 BAB12395 AB451328 BAG70142 AB451472 BAG70286 AF216305 AAF32289 AF237812 AAG09757 AI127387 AK026311 AK304656 BAG65431 AK314457 BAG37065 AK316609 BAG38196 BC005180 AAH05180 BC011007 AAH11007 BE275469 BT007053 AAP35702 XM_005260990 XP_005261047 XM_011529595 XP_011527897 XM_011529596 XP_011527898 NM_153681 NP_710148 NM_153682 NP_710149 NR_028352 |
Function | Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
DSCR 5 CRISPR/Cas9 KO Plasmid (h) - sc-412151 from Santa Cruz Biotechnology
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DSCR 5 HDR Plasmid (h) - sc-412151-HDR from Santa Cruz Biotechnology
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DSCR 5 Double Nickase Plasmid (h) - sc-412151-NIC from Santa Cruz Biotechnology
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DSCR 5 Double Nickase Plasmid (h2) - sc-412151-NIC-2 from Santa Cruz Biotechnology
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DSCR 5 CRISPR Activation Plasmid (h) - sc-412151-ACT from Santa Cruz Biotechnology
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DSCR 5 CRISPR Activation Plasmid (h2) - sc-412151-ACT-2 from Santa Cruz Biotechnology
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DSCR 5 Lentiviral Activation Particles (h) - sc-412151-LAC from Santa Cruz Biotechnology
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DSCR 5 Lentiviral Activation Particles (h2) - sc-412151-LAC-2 from Santa Cruz Biotechnology
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DSCR 5 siRNA (h) - sc-40497 from Santa Cruz Biotechnology
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DSCR 5 shRNA Plasmid (h) - sc-40497-SH from Santa Cruz Biotechnology
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DSCR 5 shRNA (h) Lentiviral Particles - sc-40497-V from Santa Cruz Biotechnology
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PIGP RNAi - H00051227-R01 from Novus Biologicals
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PIGP RNAi - H00051227-R02 from Novus Biologicals
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MISSION® esiRNA - EHU113811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16793 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16793 from Sigma-Aldrich
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PIGP siRNA (Human) - CRH9618 from Cohesion Biosciences
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shRNA set against Human PIGP (NM_153681.2) - SHH375480 from Creative biogene
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shRNA set against Human PIGP(NM_153682.2) - SHR113992 from Creative biogene
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shRNA set against Human PIGP(NM_153681.2) - SHR114126 from Creative biogene
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PIGP shRNA Plasmid (Human) - CHH9618 from Cohesion Biosciences
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PIGP miRNA 3'UTR clone - MiUTR1H-07896 from Creative biogene
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PIGP miRNA 3'UTR clone - MiUTR1H-07897 from Creative biogene
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