Gene Symbol | ROR1 |
---|---|
Entrez Gene | 4919 |
Alt Symbol | NTRKR1, dJ537F10.1 |
Species | Human |
Gene Type | protein-coding |
Description | receptor tyrosine kinase-like orphan receptor 1 |
Other Description | neurotrophic tyrosine kinase, receptor-related 1|tyrosine-protein kinase transmembrane receptor ROR1 |
Swissprots | Q01973 Q5VVX6 Q92776 Q66K77 |
Accessions | EAX06555 EAX06556 EAX06557 Q01973 AK000776 AK308088 AK309189 BC006374 BC080541 AAH80541 BC128386 AAI28387 BC156511 AAI56512 BC172555 AAI72555 M97675 AAA60275 XM_011541526 XP_011539828 NM_001083592 NP_001077061 NM_005012 NP_005003 |
Function | Tyrosine-protein kinase receptor whose role is not yet clear. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. |