| Gene Symbol |
LASP1
|
| Entrez Gene |
3927
|
| Alt Symbol |
Lasp-1, MLN50
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
LIM and SH3 protein 1
|
| Other Description |
LIM and SH3 domain protein 1|metastatic lymph node gene 50 protein
|
| Swissprots |
Q14847 B4DGQ0 Q96IG0 Q96ED2
|
| Accessions |
EAW60543 EAW60544 EAW60545 Q14847 AK095958 AK289847 BAF82536 AK294704 BAG57861 AK295522 BAG58436 AK296092 BAG58846 AK307868 AK309933 BC007367 BC007560 AAH07560 BC012460 AAH12460 BQ961916 CN371189 DC324561 DC333179 DQ891539 ABM82465 DQ894728 ABM85654 X82456 CAA57833 NM_001271608 NP_001258537 NM_006148 NP_006139 NR_073384
|
| Function |
Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cell cortex {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with the F- actin rich cortical cytoskeleton. {ECO:0000250}.
|
![Western Blot: LASP1 Overexpression Lysate (Adult Normal) [NBP2-07659] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LASP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9852_LASP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07659-img0001.jpg)