Gene Symbol | CCNB3 |
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Entrez Gene | 85417 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cyclin B3 |
Other Description | G2/mitotic-specific cyclin-B3 |
Swissprots | Q96SB6 Q9NT38 Q96SB7 B1AQI5 Q96SB5 Q8WWL7 B1AQI6 |
Accessions | EAW89920 EAW89921 EAW89922 EAW89923 Q8WWL7 AJ314764 CAC40024 AJ314765 CAC40025 AJ314766 CAC40026 AJ416458 CAC94915 AJ421672 CAD18845 AJ421673 CAD18846 AJ421674 CAD18847 AK292454 BAF85143 AL137550 CAB70806 AY927611 BC172237 AAI72237 BC172544 AAI72544 XM_006724610 XP_006724673 XM_011530832 XP_011529134 XM_011530833 XP_011529135 NM_033031 NP_149020 NM_033670 NP_391990 NM_033671 |
Function | Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I. {ECO:0000269|PubMed:12185076}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12185076}. |
Tissue Specificity | Testis specific. In testis, it is expressed in developing germ cells, but not in Leydig cells. Weakly or not expressed in other tissues. {ECO:0000269|PubMed:11846420, ECO:0000269|PubMed:12185076}. |
Top Pathways | Cell cycle, p53 signaling pathway, Progesterone-mediated oocyte maturation |
cyclin B3 CRISPR/Cas9 KO Plasmid (h) - sc-405541 from Santa Cruz Biotechnology
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cyclin B3 HDR Plasmid (h) - sc-405541-HDR from Santa Cruz Biotechnology
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cyclin B3 Double Nickase Plasmid (h) - sc-405541-NIC from Santa Cruz Biotechnology
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cyclin B3 Double Nickase Plasmid (h2) - sc-405541-NIC-2 from Santa Cruz Biotechnology
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cyclin B3 CRISPR Activation Plasmid (h) - sc-405541-ACT from Santa Cruz Biotechnology
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cyclin B3 CRISPR Activation Plasmid (h2) - sc-405541-ACT-2 from Santa Cruz Biotechnology
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cyclin B3 Lentiviral Activation Particles (h) - sc-405541-LAC from Santa Cruz Biotechnology
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cyclin B3 Lentiviral Activation Particles (h2) - sc-405541-LAC-2 from Santa Cruz Biotechnology
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cyclin B3 siRNA (h) - sc-91156 from Santa Cruz Biotechnology
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cyclin B3 shRNA Plasmid (h) - sc-91156-SH from Santa Cruz Biotechnology
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cyclin B3 shRNA (h) Lentiviral Particles - sc-91156-V from Santa Cruz Biotechnology
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CCNB3 RNAi - H00085417-R02 from Novus Biologicals
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MISSION® esiRNA - EHU081081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5630 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5630 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00941 from Sigma-Aldrich
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CCNB3 siRNA (Human) - CRJ3805 from Cohesion Biosciences
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CCNB3 RNAi - H00085417-R01 from Novus Biologicals
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CCNB3 - MBS8240243 from MyBioSource
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shRNA set against Human CCNB3 (NM_033031.2) - SHH257813 from Creative biogene
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shRNA set against Human CCNB3(NM_033670.2) - SHG152029 from Creative biogene
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shRNA set against Human CCNB3(NM_033031.2) - SHG152083 from Creative biogene
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CCNB3 shRNA Plasmid (Human) - CHJ3805 from Cohesion Biosciences
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CCNB3 miRNA 3'UTR clone - MiUTR1H-01813 from Creative biogene
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CCNB3 miRNA 3'UTR clone - MiUTR1H-01814 from Creative biogene
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