| Gene Symbol |
Aqp1
|
| Entrez Gene |
11826
|
| Alt Symbol |
CHIP28
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
aquaporin 1
|
| Other Description |
AQP-1|DER2|aquaporin-1|aquaporin-CHIP|delayed early response protein 2|growth factor-induced delayed early response protein|water channel protein for red blood cells and kidney proximal tubule
|
| Swissprots |
Q542P1 Q02013 Q91VY8
|
| Accessions |
EDK98728 Q02013 AK081886 BAC38360 AK086688 BAC39719 AK128905 AK157333 BAE34051 AK158226 BAE34412 AK158389 BAE34482 AK166280 BAE38677 AK171627 BAE42573 AK172361 BAE42966 BB850287 BC007125 AAH07125 L02914 AAB53928 NM_007472 NP_031498
|
| Function |
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. {ECO:0000269|PubMed:12133842}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:12133842}; Multi-pass membrane protein {ECO:0000269|PubMed:12133842}.
|
| Tissue Specificity |
Detected in erythrocytes (at protein level). Erythrocytes and renal tubules. {ECO:0000269|PubMed:12133842}.
|
| Top Pathways |
Proximal tubule bicarbonate reclamation, Bile secretion
|