Gene Symbol | GALNT5 |
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Entrez Gene | 11227 |
Alt Symbol | GALNAC-T5, GALNACT5 |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase 5 |
Other Description | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)|polypeptide GalNAc transferase 5|pp-GaNTase 5|protein-UDP acetylgalactosaminyltransferase 5 |
Swissprots | Q9UGK7 A5PKZ1 Q7Z7M9 Q9UHL6 |
Accessions | EAX11449 Q7Z7M9 AF154107 AAF15313 AJ245539 CAB65104 AJ505956 CAD44537 AK292154 BAF84843 AY277591 AAP34404 BC142676 AAI42677 BC142703 AAI42704 BC144211 NM_014568 NP_055383 |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2 or Muc1b substrates (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-T5 CRISPR/Cas9 KO Plasmid (h) - sc-411588 from Santa Cruz Biotechnology
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GalNAc-T5 HDR Plasmid (h) - sc-411588-HDR from Santa Cruz Biotechnology
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GalNAc-T5 Double Nickase Plasmid (h) - sc-411588-NIC from Santa Cruz Biotechnology
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GalNAc-T5 Double Nickase Plasmid (h2) - sc-411588-NIC-2 from Santa Cruz Biotechnology
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GalNAc-T5 CRISPR Activation Plasmid (h) - sc-411588-ACT from Santa Cruz Biotechnology
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GalNAc-T5 CRISPR Activation Plasmid (h2) - sc-411588-ACT-2 from Santa Cruz Biotechnology
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GalNAc-T5 Lentiviral Activation Particles (h) - sc-411588-LAC from Santa Cruz Biotechnology
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GalNAc-T5 Lentiviral Activation Particles (h2) - sc-411588-LAC-2 from Santa Cruz Biotechnology
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GalNAc-T5 siRNA (h) - sc-75098 from Santa Cruz Biotechnology
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GalNAc-T5 shRNA Plasmid (h) - sc-75098-SH from Santa Cruz Biotechnology
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GalNAc-T5 shRNA (h) Lentiviral Particles - sc-75098-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU056711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9110 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9110 from Sigma-Aldrich
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GALNT5 siRNA (Human) - CRH7694 from Cohesion Biosciences
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GALNT5 RNAi - H00011227-R01 from Novus Biologicals
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GALNT5 - MBS8212485 from MyBioSource
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shRNA set against Human Galnt5 (NM_014568.1) - SHH299065 from Creative biogene
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shRNA set against Human GALNT5(NM_014568.1) - SHH076367 from Creative biogene
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GALNT5 shRNA Plasmid (Human) - CHH7694 from Cohesion Biosciences
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GALNT5 miRNA 3'UTR clone - MiUTR1H-03940 from Creative biogene
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