Gene Symbol | BCAT2 |
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Entrez Gene | 587 |
Alt Symbol | BCAM, BCATM, BCT2, PP18 |
Species | Human |
Gene Type | protein-coding |
Description | branched chain amino-acid transaminase 2, mitochondrial |
Other Description | branched chain aminotransferase 2, mitochondrial|branched-chain-amino-acid aminotransferase, mitochondrial|placental protein 18 |
Swissprots | Q9BTB6 O00269 O15382 Q9BUU6 Q96KG1 B2RB87 |
Accessions | CBN62949 EAW52403 O15382 AF268047 AAK38368 AF268048 AAK38369 AK023909 AK093627 BAG52745 AK223522 BAD97242 AK309428 AK310101 AK310243 AK314548 BAG37134 BC001900 AAH01900 BC004243 AAH04243 BE139200 BM802402 BU178552 CA310873 CB049110 DA129578 DC395685 DQ892350 ABM83276 DQ895554 ABM86480 U62739 AAB53087 U68418 AAB67672 NM_001164773 NP_001158245 NM_001190 NP_001181 NM_001284325 NP_001271254 NR_028451 |
Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. |
Subcellular Location | Isoform A: Mitochondrion. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Valine, leucine and isoleucine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Valine, leucine and isoleucine degradation, Pantothenate and CoA biosynthesis |
BCAT2 CRISPR/Cas9 KO Plasmid (h) - sc-410701 from Santa Cruz Biotechnology
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BCAT2 HDR Plasmid (h) - sc-410701-HDR from Santa Cruz Biotechnology
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BCAT2 Double Nickase Plasmid (h) - sc-410701-NIC from Santa Cruz Biotechnology
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BCAT2 Double Nickase Plasmid (h2) - sc-410701-NIC-2 from Santa Cruz Biotechnology
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BCAT2 CRISPR Activation Plasmid (h) - sc-410701-ACT from Santa Cruz Biotechnology
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BCAT2 CRISPR Activation Plasmid (h2) - sc-410701-ACT-2 from Santa Cruz Biotechnology
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BCAT2 Lentiviral Activation Particles (h) - sc-410701-LAC from Santa Cruz Biotechnology
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BCAT2 Lentiviral Activation Particles (h2) - sc-410701-LAC-2 from Santa Cruz Biotechnology
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BCAT2 siRNA (h) - sc-97896 from Santa Cruz Biotechnology
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BCAT2 shRNA Plasmid (h) - sc-97896-SH from Santa Cruz Biotechnology
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BCAT2 shRNA (h) Lentiviral Particles - sc-97896-V from Santa Cruz Biotechnology
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BCAM/CD239 RNAi - H00004059-R04 from Novus Biologicals
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BCAM/CD239 RNAi - H00004059-R03 from Novus Biologicals
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MISSION® esiRNA - EHU032991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3897 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3897 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03207 from Sigma-Aldrich
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BCAT2 siRNA (Human) - CRH0404 from Cohesion Biosciences
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BCAT2 - MBS8237749 from MyBioSource
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shRNA set against Human BCAT2 (NM_001190.3) - SHH245762 from Creative biogene
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Human BCAT2 siRNA - orb260906 from Biorbyt
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BCAT2 shRNA Plasmid (Human) - CHH0404 from Cohesion Biosciences
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BCAT2 miRNA 3'UTR clone - MiUTR3H-00284 from Creative biogene
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BCAT2 miRNA 3'UTR clone - MiUTR3H-00285 from Creative biogene
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