Aox3

Gene Symbol Aox3
Entrez Gene 71724
Alt Symbol 1200011D03Rik, AI326299, Aoh1, Aoh2
Species Mouse
Gene Type protein-coding
Description aldehyde oxidase 3
Other Description aldehyde oxidase 1|aldehyde oxidase homolog 1|aldehyde oxidase structural homolog 2|azaheterocycle hydroxylase 3
Swissprots B2RSI5 G3X982 Q8VI15
Accessions AAL36596 AAQ24539 AAQ24540 EDL00068 EDL00069 G3X982 AF172276 AAD51028 AK004700 BAB23485 AK030109 AK050061 AK054065 BAC35643 AK143048 AK149434 AV275739 AY347569 AAQ24537 AY347570 AAQ24538 BB616838 BC024046 BC049853 BC138876 AAI38877 BX633666 XM_006496284 XP_006496347 XM_006496285 XP_006496348 NM_023617 NP_076106
Function Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and phthalazine, as well as aldehydes, such as benzaldehyde, retinal and pyridoxal. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. {ECO:0000269|PubMed:11562361, ECO:0000269|PubMed:18981221, ECO:0000269|PubMed:21705476, ECO:0000269|PubMed:23019336}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11562361, ECO:0000269|PubMed:15383531}.
Tissue Specificity Highly expressed in liver (at protein level). In liver, the expression is greater in males than females. {ECO:0000269|PubMed:11562361, ECO:0000269|PubMed:15383531, ECO:0000269|PubMed:18981221}.
Top Pathways Tyrosine metabolism, Vitamin B6 metabolism, Nicotinate and nicotinamide metabolism, Retinol metabolism, Tryptophan metabolism

AOX3 CRISPR/Cas9 KO Plasmid (m) - sc-428026 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 HDR Plasmid (m) - sc-428026-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 Double Nickase Plasmid (m) - sc-428026-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 Double Nickase Plasmid (m2) - sc-428026-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 CRISPR Activation Plasmid (m) - sc-428026-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 CRISPR Activation Plasmid (m2) - sc-428026-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 Lentiviral Activation Particles (m) - sc-428026-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 Lentiviral Activation Particles (m2) - sc-428026-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

AOX3 siRNA (m) - sc-141129 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

AOX3 shRNA Plasmid (m) - sc-141129-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

AOX3 shRNA (m) Lentiviral Particles - sc-141129-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU039921 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN26780 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26780 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AOX3 siRNA (Mouse) - CRM8504 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

AOX3 - MBS8209998 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Aox3 (NM_023617.2) - SHH237698 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Aox3(NM_023617.2) - SHG062753 from Creative biogene

Category siRNA
Species Reactivities Mouse

AOX3 shRNA Plasmid (Mouse) - CHM8504 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

AOX3 miRNA 3'UTR clone - MiUTR1M-01534 from Creative biogene

Species Reactivities Mouse
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