Gene Symbol | NDUFS7 |
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Entrez Gene | 374291 |
Alt Symbol | CI-20, CI-20KD, MY017, PSST |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) |
Other Description | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial|NADH-coenzyme Q reductase|NADH-ubiquinone oxidoreductase 20 kDa subunit|NADH:ubiquinone oxidoreductase PSST subunit|PSST subunit|complex I 20kDa subunit|complex I, mitochondrial respiratory chain, 20-KD subunit|complex I-20kD |
Swissprots | Q9BV17 Q2T9H7 B3KRI2 O75251 |
Accessions | AAC27669 EAW69507 EAW69508 O75251 AF060512 AAG43130 AF115969 AAP97240 AK056061 AK091024 AK091046 AK091623 BAG52394 AK092169 BAC03820 AK127759 BAC87117 AK128713 BAC87587 AK222738 BAD96458 AK289671 BAF82360 AK293917 BAH11627 AK297611 BAH12627 BC001715 AAH01715 BC005954 AAH05954 BC111517 AAI11518 BX099945 DC340464 JF432732 ADZ15949 XM_005259556 XP_005259613 NM_024407 NP_077718 |
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFS7 CRISPR/Cas9 KO Plasmid (h) - sc-408363 from Santa Cruz Biotechnology
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NDUFS7 HDR Plasmid (h) - sc-408363-HDR from Santa Cruz Biotechnology
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NDUFS7 Double Nickase Plasmid (h) - sc-408363-NIC from Santa Cruz Biotechnology
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NDUFS7 Double Nickase Plasmid (h2) - sc-408363-NIC-2 from Santa Cruz Biotechnology
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NDUFS7 CRISPR Activation Plasmid (h) - sc-408363-ACT from Santa Cruz Biotechnology
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NDUFS7 CRISPR Activation Plasmid (h2) - sc-408363-ACT-2 from Santa Cruz Biotechnology
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NDUFS7 Lentiviral Activation Particles (h) - sc-408363-LAC from Santa Cruz Biotechnology
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NDUFS7 Lentiviral Activation Particles (h2) - sc-408363-LAC-2 from Santa Cruz Biotechnology
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NDUFS7 siRNA (h) - sc-97909 from Santa Cruz Biotechnology
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NDUFS7 shRNA Plasmid (h) - sc-97909-SH from Santa Cruz Biotechnology
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NDUFS7 shRNA (h) Lentiviral Particles - sc-97909-V from Santa Cruz Biotechnology
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NDUFS7 RNAi - H00374291-R01 from Novus Biologicals
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MISSION® esiRNA - EHU125051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15172 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15172 from Sigma-Aldrich
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NDUFS7 siRNA (Human) - CRJ7609 from Cohesion Biosciences
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shRNA set against Human NDUFS7 (NM_024407.4) - SHH350912 from Creative biogene
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Human NDUFS7 siRNA - orb278110 from Biorbyt
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NDUFS7 shRNA Plasmid (Human) - CHJ7609 from Cohesion Biosciences
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NDUFS7 miRNA 3'UTR clone - MiUTR3H-04435 from Creative biogene
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