Gene Symbol | NDUFB5 |
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Entrez Gene | 4711 |
Alt Symbol | CISGDH, SGDH |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial|NADH-ubiquinone oxidoreductase SGDH subunit|complex I SGDH subunit|complex I-SGDH |
Swissprots | Q561V6 O43674 |
Accessions | EAW78385 EAW78386 EAW78387 EAW78388 EAW78389 EAW78390 EAW78391 EAW78392 EAW78393 O43674 AF047181 AAC04266 AK055159 BAB70865 AK313822 BAG36557 AW955118 BC005271 AAH05271 BC009796 AAH09796 BC017909 AAH17909 BC093071 AAH93071 BG776403 BX648034 CD364869 DA112751 HQ448677 ADQ33155 NM_001199957 NP_001186886 NM_001199958 NP_001186887 NM_002492 NP_002483 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB5 CRISPR/Cas9 KO Plasmid (h) - sc-410902 from Santa Cruz Biotechnology
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NDUFB5 HDR Plasmid (h) - sc-410902-HDR from Santa Cruz Biotechnology
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NDUFB5 Double Nickase Plasmid (h) - sc-410902-NIC from Santa Cruz Biotechnology
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NDUFB5 Double Nickase Plasmid (h2) - sc-410902-NIC-2 from Santa Cruz Biotechnology
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NDUFB5 CRISPR Activation Plasmid (h) - sc-410902-ACT from Santa Cruz Biotechnology
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NDUFB5 CRISPR Activation Plasmid (h2) - sc-410902-ACT-2 from Santa Cruz Biotechnology
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NDUFB5 Lentiviral Activation Particles (h) - sc-410902-LAC from Santa Cruz Biotechnology
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NDUFB5 Lentiviral Activation Particles (h2) - sc-410902-LAC-2 from Santa Cruz Biotechnology
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NDUFB5 siRNA (h) - sc-78552 from Santa Cruz Biotechnology
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NDUFB5 shRNA Plasmid (h) - sc-78552-SH from Santa Cruz Biotechnology
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NDUFB5 shRNA (h) Lentiviral Particles - sc-78552-V from Santa Cruz Biotechnology
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NDUFB5 RNAi - H00004711-R01 from Novus Biologicals
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MISSION® esiRNA - EHU141141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15159 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15159 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04540 from Sigma-Aldrich
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NDUFB5 siRNA (Human) - CRH3125 from Cohesion Biosciences
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shRNA set against Human NDUFB5 (NM_002492.3) - SHH350756 from Creative biogene
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Human NDUFB5 siRNA - orb263627 from Biorbyt
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NDUFB5 shRNA Plasmid (Human) - CHH3125 from Cohesion Biosciences
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NDUFB5 miRNA 3'UTR clone - MiUTR3H-06309 from Creative biogene
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