| Gene Symbol |
ERF
|
| Entrez Gene |
2077
|
| Alt Symbol |
CRS4, PE-2, PE2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Ets2 repressor factor
|
| Other Description |
ETS domain-containing transcription factor ERF
|
| Swissprots |
B2RAP1 Q9UPI7 Q59G38 B7Z4R0 P50548
|
| Accessions |
AAD11987 EAW57116 EAW57117 EAW57118 P50548 AA961500 AB209271 BAD92508 AK297666 BAH12646 AK300627 BAH13317 AK314278 BAG36938 AW005463 BC022231 AAH22231 BM905776 DC299706 DC371332 DC407368 DQ893568 ABM84494 DQ896817 ABM87816 U15655 AAA86686 XM_005258644 XP_005258701 XM_006723079 XP_006723142 XM_011526612 XP_011524914 XM_011526613 XP_011524915 NM_001301035 NP_001287964 NM_001308402 NP_001295331 NM_006494 NP_006485
|
| Function |
Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Highest levels in testis, ovary, pancreas, and heart. {ECO:0000269|PubMed:9192842}.
|