| Gene Symbol | Cnot11 |
|---|---|
| Entrez Gene | 363221 |
| Alt Symbol | RGD1560909 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | CCR4-NOT transcription complex, subunit 11 |
| Other Description | CCR4-NOT transcription complex subunit 11|UPF0760 protein C2orf29 homolog |
| Swissprots | B0BNA9 |
| Accessions | B0BNA9 EDL99194 EDL99195 BC158750 AAI58751 FQ233266 NM_001108794 NP_001102264 |
| Function | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
CompoZr® Knockout ZFN Kit - CKOZFN61635 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND61635 from Sigma-Aldrich
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CNOT11 siRNA (Rat) - CRR6172 from Cohesion Biosciences
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CNOT11 - MBS8204894 from MyBioSource
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shRNA set against Rat RGD1560909 (NM_001108794.2) - SHH393868 from Creative biogene
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CNOT11 shRNA Plasmid (Rat) - CHR6172 from Cohesion Biosciences
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