Gene Symbol | SUGCT |
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Entrez Gene | 79783 |
Alt Symbol | C7orf10, DERP13, ORF19 |
Species | Human |
Gene Type | protein-coding |
Description | succinyl-CoA:glutarate-CoA transferase |
Other Description | Russel-Silver syndrome candidate|dermal papilla-derived protein 13|succinate--hydroxymethylglutarate CoA-transferase|succinylCoA:glutarate-CoA transferase |
Swissprots | Q4KMW4 A4D1W5 Q8TE00 Q4KMZ0 Q9HAC7 Q8TEY1 Q4KMW8 B4DR73 |
Accessions | AAD26979 AAS01999 AAS02000 AAS07506 EAL24000 EAW94135 EAW94136 EAW94137 Q9HAC7 AB014767 BAB87807 AF086161 AF397013 AAL76418 AK021870 BAB13922 AK296048 BAG58812 AK298516 BAH12804 AK299133 BAG61185 AK307935 AK308764 BC098117 AAH98117 BC098261 AAH98261 BC098310 AAH98310 BC098318 AAH98318 BM668297 XM_006715775 XP_006715838 XM_011515525 XP_011513827 XM_011515526 XP_011513828 XM_011515527 XP_011513829 XM_011515528 XP_011513830 XM_011515529 XP_011513831 XM_011515530 XP_011513832 NM_001193311 NP_001180240 NM_001193312 NP_001180241 NM_001193313 NP_001180242 NM_024728 NP_079004 |
Function | Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate. {ECO:0000269|PubMed:23893049}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:23893049}. |
Tissue Specificity | Highly expressed in kidney. Intermediate expression in liver, skeletal muscle and pancreas. Little to no expression detected in other tissues examined. {ECO:0000269|PubMed:11829489}. |
C7orf10 siRNA (h) - sc-89344 from Santa Cruz Biotechnology
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C7orf10 shRNA Plasmid (h) - sc-89344-SH from Santa Cruz Biotechnology
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C7orf10 shRNA (h) Lentiviral Particles - sc-89344-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN5078 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5078 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01711 from Sigma-Aldrich
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SUGCT siRNA (Human) - CRJ2560 from Cohesion Biosciences
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SUGCT - MBS8218522 from MyBioSource
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shRNA set against Human C7orf10 (NM_024728.2) - SHH252389 from Creative biogene
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Human SUGCT siRNA - orb273061 from Biorbyt
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SUGCT shRNA Plasmid (Human) - CHJ2560 from Cohesion Biosciences
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C7ORF10 miRNA 3'UTR clone - MiUTR4H-TG01140 from Creative biogene
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