| Gene Symbol |
ORC5
|
| Entrez Gene |
5001
|
| Alt Symbol |
ORC5L, ORC5P, ORC5T, PPP1R117
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
origin recognition complex, subunit 5
|
| Other Description |
origin recognition complex subunit 5|protein phosphatase 1, regulatory subunit 117
|
| Swissprots |
A4D0P8 O95268 O43913 O60590
|
| Accessions |
AAF19238 AAM49152 EAL24408 EAL24409 EAW83341 EAW83342 EAW83343 O43913 AF047599 AAC80283 AF049127 AAC63972 AF081459 AAC64401 AK223361 BAD97081 AK292285 BAF84974 AK302122 BAG63500 AK313596 BAG36362 BC023652 AAH23652 BF678849 DQ892274 ABM83200 DQ895475 ABM86401 U92538 AAC51933 XM_006716015 XP_006716078 XM_011516273 XP_011514575 NM_002553 NP_002544 NM_181747 NP_859531 NM_001197292
|
| Function |
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Abundant in spleen, ovary, prostate, testis, and colon mucosa. {ECO:0000269|PubMed:9765232}.
|
| Top Pathways |
Cell cycle
|