| Gene Symbol |
ADAMTS3
|
| Entrez Gene |
9508
|
| Alt Symbol |
ADAMTS-4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADAM metallopeptidase with thrombospondin type 1 motif, 3
|
| Other Description |
A disintegrin and metalloproteinase with thrombospondin motifs 3|ADAM-TS 3|ADAM-TS3|ADAMTS-3|PC II-NP|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3|procollagen II N-proteinase|procollagen II amino propeptide-processing enzyme|zinc metalloendopeptidase
|
| Swissprots |
O15072 Q9BXZ8 A1L3U9
|
| Accessions |
EAX05651 EAX05652 O15072 AB002364 BAA20821 AF247668 AAK28400 AK295131 BAH11985 BC016451 AAH16451 BC019707 BC130287 AAI30288 BC132735 AAI32736 XM_011532421 XP_011530723 XM_011532422 XP_011530724 XM_011532423 XP_011530725 XM_011532424 XP_011530726 NM_014243 NP_055058
|
| Function |
Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|
| Tissue Specificity |
Found in cartilage and skin.
|
![Western Blot: ADAMTS3 Overexpression Lysate (Adult Normal) [NBP2-07367] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ADAMTS3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1763_ADAMTS3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07367-img0001.jpg)