Gene Symbol | ACSBG2 |
---|---|
Entrez Gene | 81616 |
Alt Symbol | BGR, BRGL, PRTD-NY3, PRTDNY3 |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA synthetase bubblegum family member 2 |
Other Description | bubblegum-related protein|long-chain-fatty-acid--CoA ligase ACSBG2 |
Swissprots | Q8WW03 Q6UWJ3 Q5FVE4 Q9H0C4 Q96M36 Q9BYZ3 B3KSF2 Q7Z5A0 |
Accessions | CBH19185 EAW69111 Q5FVE4 AJ577571 CAE12156 AK057412 BAB71476 AK093433 BAG52714 AK225862 AK302604 BAG63853 AL040604 AL136854 CAB66788 AY009107 AAG49398 AY358766 AAQ89126 BC022027 AAH22027 BC090046 AAH90046 BI561348 DB514968 DC399703 DQ890833 ABM81759 DQ893988 ABM84914 EU831601 ACE87201 EU831688 ACE86522 HY011431 XM_005259653 XP_005259710 XM_006722915 XP_006722978 XM_011528327 XP_011526629 XM_011528328 XP_011526630 XM_011528329 XP_011526631 NM_001289177 NP_001276106 NM_001289178 NP_001276107 NM_001289179 NP_001276108 NM_001289180 NP_001276109 NM_030924 NP_112186 |
Function | Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. |
Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:15685348, ECO:0000269|PubMed:16371355, ECO:0000269|PubMed:16762313}. |
Top Pathways | Adipocytokine signaling pathway, PPAR signaling pathway, Fatty acid biosynthesis, Fatty acid degradation, Fatty acid metabolism |
ACSBG2 CRISPR/Cas9 KO Plasmid (h) - sc-413440 from Santa Cruz Biotechnology
|
||||||||
ACSBG2 HDR Plasmid (h) - sc-413440-HDR from Santa Cruz Biotechnology
|
||||||||
ACSBG2 Double Nickase Plasmid (h) - sc-413440-NIC from Santa Cruz Biotechnology
|
||||||||
ACSBG2 Double Nickase Plasmid (h2) - sc-413440-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ACSBG2 CRISPR Activation Plasmid (h) - sc-413440-ACT from Santa Cruz Biotechnology
|
||||||||
ACSBG2 CRISPR Activation Plasmid (h2) - sc-413440-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ACSBG2 Lentiviral Activation Particles (h) - sc-413440-LAC from Santa Cruz Biotechnology
|
||||||||
ACSBG2 Lentiviral Activation Particles (h2) - sc-413440-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ACSBG2 siRNA (h) - sc-97139 from Santa Cruz Biotechnology
|
||||||||
ACSBG2 shRNA Plasmid (h) - sc-97139-SH from Santa Cruz Biotechnology
|
||||||||
ACSBG2 shRNA (h) Lentiviral Particles - sc-97139-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU012951 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN2749 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2749 from Sigma-Aldrich
|
||||||||
ACSBG2 siRNA (Human) - CRJ3024 from Cohesion Biosciences
|
||||||||
ACSBG2 - MBS8222177 from MyBioSource
|
||||||||
shRNA set against Human ACSBG2 (NM_030924.3) - SHH230686 from Creative biogene
|
||||||||
shRNA set against Human ACSBG2(NM_030924.3) - SHG035385 from Creative biogene
|
||||||||
Human ACSBG2 siRNA - orb273525 from Biorbyt
|
||||||||
ACSBG2 shRNA Plasmid (Human) - CHJ3024 from Cohesion Biosciences
|
||||||||
ACSBG2 miRNA 3'UTR clone - MiUTR1H-00120 from Creative biogene
|