| Gene Symbol | Trxr-2 |
|---|---|
| Entrez Gene | 40475 |
| Alt Symbol | CG11401, Dm-TrxR, DmTrx, DmTrxR-2, Dmel\CG11401, TRR, TrxR, Trxr2, trxr-2 |
| Species | Drosophila |
| Gene Type | protein-coding |
| Description | thioredoxin reductase 2 |
| Other Description | CG11401-PA|Trxr-2-PA|thioredoxin reductase|thioredoxin-reductase-2 |
| Swissprots | Q9VNT5 |
| Accessions | AAF51835 AAF64152 Q9VNT5 AY121613 AAM51940 NM_079492 NP_524216 |
| Function | Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms. {ECO:0000250|UniProtKB:P91938}. |
| Subcellular Location | Mitochondrion. |
| Top Pathways | Selenocompound metabolism, Pyrimidine metabolism |