| Gene Symbol |
Trxr-2
|
| Entrez Gene |
40475
|
| Alt Symbol |
CG11401, Dm-TrxR, DmTrx, DmTrxR-2, Dmel\CG11401, TRR, TrxR, Trxr2, trxr-2
|
| Species |
Drosophila
|
| Gene Type |
protein-coding
|
| Description |
thioredoxin reductase 2
|
| Other Description |
CG11401-PA|Trxr-2-PA|thioredoxin reductase|thioredoxin-reductase-2
|
| Swissprots |
Q9VNT5
|
| Accessions |
AAF51835 AAF64152 Q9VNT5 AY121613 AAM51940 NM_079492 NP_524216
|
| Function |
Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms. {ECO:0000250|UniProtKB:P91938}.
|
| Subcellular Location |
Mitochondrion.
|
| Top Pathways |
Selenocompound metabolism, Pyrimidine metabolism
|