Gene Symbol | PHF6 |
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Entrez Gene | 84295 |
Alt Symbol | BFLS, BORJ, CENP-31 |
Species | Human |
Gene Type | protein-coding |
Description | PHD finger protein 6 |
Other Description | PHD-like zinc finger protein|centromere protein 31 |
Swissprots | Q5JRC7 Q8IWS0 B4E0G4 D3DTG3 Q96JK3 A8K230 E9PC97 Q9BRU0 Q5JRC8 |
Accessions | EAX11762 EAX11763 EAX11764 EAX11765 EAX11766 Q8IWS0 AB058726 BAB47452 AK290095 BAF82784 AK303369 BAG64426 AK303647 BAG64650 AL832725 AW297001 AY157622 AAO13214 BC005994 AAH05994 BG122271 CD685336 CF242973 DR000282 HQ448201 ADQ32682 NM_001015877 NP_001015877 NM_032335 NP_115711 NM_032458 NP_115834 |
Function | Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription. {ECO:0000269|PubMed:23229552}. |
Subcellular Location | Nucleus. Nucleus, nucleolus. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}. Note=Nuclear, it particularly localizes to the nucleolus. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12415272}. |
PHF6 CRISPR/Cas9 KO Plasmid (h) - sc-413618 from Santa Cruz Biotechnology
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PHF6 HDR Plasmid (h) - sc-413618-HDR from Santa Cruz Biotechnology
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PHF6 Double Nickase Plasmid (h) - sc-413618-NIC from Santa Cruz Biotechnology
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PHF6 Double Nickase Plasmid (h2) - sc-413618-NIC-2 from Santa Cruz Biotechnology
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PHF6 CRISPR Activation Plasmid (h) - sc-413618-ACT from Santa Cruz Biotechnology
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PHF6 CRISPR Activation Plasmid (h2) - sc-413618-ACT-2 from Santa Cruz Biotechnology
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PHF6 Lentiviral Activation Particles (h) - sc-413618-LAC from Santa Cruz Biotechnology
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PHF6 Lentiviral Activation Particles (h2) - sc-413618-LAC-2 from Santa Cruz Biotechnology
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PHF6 siRNA (h) - sc-90882 from Santa Cruz Biotechnology
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PHF6 shRNA Plasmid (h) - sc-90882-SH from Santa Cruz Biotechnology
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PHF6 shRNA (h) Lentiviral Particles - sc-90882-V from Santa Cruz Biotechnology
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PHF6 RNAi - H00084295-R03 from Novus Biologicals
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PHF6 RNAi - H00084295-R01 from Novus Biologicals
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PHF6 RNAi - H00084295-R02 from Novus Biologicals
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MISSION® esiRNA - EHU066941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16733 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16733 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR14100 from Sigma-Aldrich
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PHF6 siRNA (Human) - CRJ3419 from Cohesion Biosciences
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shRNA set against Human PHF6 (NM_032458.2) - SHH374812 from Creative biogene
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shRNA set against Human PHF6(NM_032458.2) - SHR111632 from Creative biogene
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shRNA set against Human PHF6(NM_001015877.1) - SHR111650 from Creative biogene
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Human PHF6 siRNA - orb273920 from Biorbyt
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PHF6 shRNA Plasmid (Human) - CHJ3419 from Cohesion Biosciences
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PHF6 miRNA 3'UTR clone - MiUTR1H-07864 from Creative biogene
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