Gene Symbol | SH3GL2 |
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Entrez Gene | 6456 |
Alt Symbol | CNSA2, EEN-B1, SH3D2A, SH3P4 |
Species | Human |
Gene Type | protein-coding |
Description | SH3-domain GRB2-like 2 |
Other Description | Endophilin A1 BAR domain|SH3 domain protein 2A|SH3 domain-containing GRB2-like protein 2|bA335L15.1 (SH3-domain GRB2-like 2)|endophilin-1|endophilin-A1 |
Swissprots | B2R618 Q9NQK5 Q99962 |
Accessions | ABS52637 EAW58661 EAW58662 EAW58663 Q99962 AB206840 BAE44459 AF036268 AAC04764 AK057744 AK293546 BAH11530 AK293592 BAH11542 AK302273 BAH13663 AK302572 BAH13749 AK312400 BAG35315 AW149386 AW615196 BC032825 AAH32825 BT019682 AAV38488 BX538074 CAD97999 CR542086 CAG46883 CR542102 CAG46899 DC309737 X99657 CAA67971 XM_005251549 XP_005251606 XM_011518005 XP_011516307 NM_003026 NP_003017 |
Function | Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Concentrated in presynaptic nerve terminals in neurons. |
Tissue Specificity | Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum. |
Top Pathways | Endocytosis |
Endophilin I CRISPR/Cas9 KO Plasmid (h) - sc-402069 from Santa Cruz Biotechnology
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Endophilin I HDR Plasmid (h) - sc-402069-HDR from Santa Cruz Biotechnology
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Endophilin I Double Nickase Plasmid (h) - sc-402069-NIC from Santa Cruz Biotechnology
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Endophilin I Double Nickase Plasmid (h2) - sc-402069-NIC-2 from Santa Cruz Biotechnology
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Endophilin I CRISPR Activation Plasmid (h) - sc-402069-ACT from Santa Cruz Biotechnology
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Endophilin I CRISPR Activation Plasmid (h2) - sc-402069-ACT-2 from Santa Cruz Biotechnology
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Endophilin I Lentiviral Activation Particles (h) - sc-402069-LAC from Santa Cruz Biotechnology
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Endophilin I Lentiviral Activation Particles (h2) - sc-402069-LAC-2 from Santa Cruz Biotechnology
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Endophilin I siRNA (h) - sc-35304 from Santa Cruz Biotechnology
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Endophilin I shRNA Plasmid (h) - sc-35304-SH from Santa Cruz Biotechnology
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Endophilin I shRNA (h) Lentiviral Particles - sc-35304-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU045491 from Sigma-Aldrich
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MISSION® esiRNA - EHU034551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19271 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09562 from Sigma-Aldrich
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SH3GL2 siRNA (Human) - CRH4366 from Cohesion Biosciences
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Endophilin A1/SH3GL2 RNAi - H00006456-R01 from Novus Biologicals
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SH3GL2 - MBS8241217 from MyBioSource
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shRNA set against Human SH3GL2 (NM_003026.2) - SHH406752 from Creative biogene
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SH3GL2 shRNA Plasmid (Human) - CHH4366 from Cohesion Biosciences
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SH3GL2 miRNA 3'UTR clone - MiUTR3H-06826 from Creative biogene
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