Gene Symbol | PTS |
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Entrez Gene | 5805 |
Alt Symbol | PTPS |
Species | Human |
Gene Type | protein-coding |
Description | 6-pyruvoyltetrahydropterin synthase |
Other Description | 6-pyruvoyl tetrahydrobiopterin synthase|PTP synthase |
Swissprots | B0YJ87 Q8WVG8 Q03393 |
Accessions | AAB64229 AAC16970 ACA06065 BAA04959 BAA95486 EAW67195 Q03393 AK307133 AK310768 AM392676 CAL37554 AM393300 CAL38178 AM393668 CAL38544 BC009686 AAH09686 BC018029 AAH18029 CF529329 D17400 BAA04224 DQ890961 ABM81887 DQ894133 ABM85059 M97655 AAA51541 XM_011542943 XP_011541245 NM_000317 NP_000308 |
Function | Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6- pyruvoyl tetrahydropterin. {ECO:0000269|PubMed:1282802}. |
Top Pathways | Folate biosynthesis |
PTPS CRISPR/Cas9 KO Plasmid (h) - sc-406618 from Santa Cruz Biotechnology
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PTPS HDR Plasmid (h) - sc-406618-HDR from Santa Cruz Biotechnology
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PTPS Double Nickase Plasmid (h) - sc-406618-NIC from Santa Cruz Biotechnology
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PTPS Double Nickase Plasmid (h2) - sc-406618-NIC-2 from Santa Cruz Biotechnology
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PTPS CRISPR Activation Plasmid (h) - sc-406618-ACT from Santa Cruz Biotechnology
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PTPS CRISPR Activation Plasmid (h2) - sc-406618-ACT-2 from Santa Cruz Biotechnology
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PTPS Lentiviral Activation Particles (h) - sc-406618-LAC from Santa Cruz Biotechnology
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PTPS Lentiviral Activation Particles (h2) - sc-406618-LAC-2 from Santa Cruz Biotechnology
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PTPS siRNA (h) - sc-106734 from Santa Cruz Biotechnology
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PTPS shRNA Plasmid (h) - sc-106734-SH from Santa Cruz Biotechnology
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PTPS shRNA (h) Lentiviral Particles - sc-106734-V from Santa Cruz Biotechnology
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PTS RNAi - H00005805-R01 from Novus Biologicals
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MISSION® esiRNA - EHU050831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17727 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17727 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04415 from Sigma-Aldrich
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PTS siRNA (Human) - CRH3926 from Cohesion Biosciences
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shRNA set against Human PTS (NM_000317.2) - SHH386944 from Creative biogene
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shRNA set against Human PTS(NM_000317.2) - SHR154290 from Creative biogene
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PTS shRNA Plasmid (Human) - CHH3926 from Cohesion Biosciences
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PTS miRNA 3'UTR clone - MiUTR3H-12563 from Creative biogene
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