Gene Symbol | Flt3l |
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Entrez Gene | 14256 |
Alt Symbol | Flt3lg, Ly72L |
Species | Mouse |
Gene Type | protein-coding |
Description | FMS-like tyrosine kinase 3 ligand |
Other Description | flt3 ligand|fms-related tyrosine kinase 3 ligand |
Swissprots | P49772 Q64085 |
Accessions | AAA90951 AAA90952 AAA93305 AAA93306 AAA93307 EDL22807 EDL22808 EDL22809 EDL22810 EDL22811 EDL22812 EDL22813 P49772 AK020105 BAB31997 BB224229 BC019801 AAH19801 CK622267 EU274583 ABX76044 L23636 AAA39436 S76459 AAB33069 S76461 AAB33070 S76464 AAB33071 U04807 AAA18000 XM_006540606 XP_006540669 XM_006540607 XP_006540670 XM_006540608 XP_006540671 XM_006540609 XP_006540672 XM_006540610 XP_006540673 XM_006540612 XP_006540675 XM_011250793 XP_011249095 XM_011250794 XP_011249096 XR_882010 XR_882011 XR_882012 XR_882013 XR_882014 XR_882015 XR_882016 XR_882017 XR_882018 XR_882019 NM_013520 NP_038548 NR_102725 |
Function | Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. |
Subcellular Location | Isoform 4: Secreted. Note=Inactive. |
Top Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage |
Flt 3-L CRISPR/Cas9 KO Plasmid (m) - sc-420385 from Santa Cruz Biotechnology
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Flt 3-L HDR Plasmid (m) - sc-420385-HDR from Santa Cruz Biotechnology
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Flt 3-L Double Nickase Plasmid (m) - sc-420385-NIC from Santa Cruz Biotechnology
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Flt 3-L Double Nickase Plasmid (m2) - sc-420385-NIC-2 from Santa Cruz Biotechnology
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Flt 3-L CRISPR Activation Plasmid (m) - sc-420385-ACT from Santa Cruz Biotechnology
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Flt 3-L CRISPR Activation Plasmid (m2) - sc-420385-ACT-2 from Santa Cruz Biotechnology
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Flt 3-L Lentiviral Activation Particles (m) - sc-420385-LAC from Santa Cruz Biotechnology
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Flt 3-L Lentiviral Activation Particles (m2) - sc-420385-LAC-2 from Santa Cruz Biotechnology
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Flt 3-L siRNA (m) - sc-39489 from Santa Cruz Biotechnology
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Flt 3-L shRNA Plasmid (m) - sc-39489-SH from Santa Cruz Biotechnology
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Flt 3-L shRNA (m) Lentiviral Particles - sc-39489-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN31442 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31442 from Sigma-Aldrich
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FLT3LG siRNA (Mouse) - CRM1396 from Cohesion Biosciences
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FLT3LG - MBS8214756 from MyBioSource
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shRNA set against Mouse Flt3l (NM_013520.3) - SHH295785 from Creative biogene
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Mouse FLT3LG siRNA - orb280872 from Biorbyt
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FLT3LG shRNA Plasmid (Mouse) - CHM1396 from Cohesion Biosciences
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