Gene Symbol | EBP |
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Entrez Gene | 10682 |
Alt Symbol | CDPX2, CHO2, CPX, CPXD |
Species | Human |
Gene Type | protein-coding |
Description | emopamil binding protein (sterol isomerase) |
Other Description | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase|3-beta-hydroxysteroid-delta-8,delta-7-isomerase|Chondrodysplasia punctata-2, X-linked dominant (Happle syndrome)|D8-D7 sterol isomerase|cholestenol Delta-isomerase|delta(8)-Delta(7) sterol isomerase|emopamil-binding protein (sterol isomerase)|sterol 8-isomerase |
Swissprots | Q6FGL3 Q6IBI9 Q15125 |
Accessions | CAE83482 EAW50773 EAW50774 EAW50775 Q15125 AU128761 BC001549 AAH01549 BC001572 AAH01572 BC046501 AAH46501 CA488777 CR456815 CAG33096 CR542094 CAG46891 DQ891591 ABM82517 DQ894785 ABM85711 DQ894786 ABM85712 KJ921656 AIL31429 Z37986 CAA86068 NM_006579 NP_006570 |
Function | Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Top Pathways | Steroid biosynthesis |
EBP CRISPR/Cas9 KO Plasmid (h) - sc-411503 from Santa Cruz Biotechnology
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EBP HDR Plasmid (h) - sc-411503-HDR from Santa Cruz Biotechnology
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EBP Double Nickase Plasmid (h) - sc-411503-NIC from Santa Cruz Biotechnology
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EBP Double Nickase Plasmid (h2) - sc-411503-NIC-2 from Santa Cruz Biotechnology
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EBP CRISPR Activation Plasmid (h) - sc-411503-ACT from Santa Cruz Biotechnology
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EBP CRISPR Activation Plasmid (h2) - sc-411503-ACT-2 from Santa Cruz Biotechnology
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EBP Lentiviral Activation Particles (h) - sc-411503-LAC from Santa Cruz Biotechnology
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EBP Lentiviral Activation Particles (h2) - sc-411503-LAC-2 from Santa Cruz Biotechnology
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EBP siRNA (h) - sc-77218 from Santa Cruz Biotechnology
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EBP shRNA Plasmid (h) - sc-77218-SH from Santa Cruz Biotechnology
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EBP shRNA (h) Lentiviral Particles - sc-77218-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU014361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7625 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7625 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01884 from Sigma-Aldrich
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EBP siRNA (Human) - CRH7285 from Cohesion Biosciences
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EBP - MBS8200242 from MyBioSource
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shRNA set against Human EBP (NM_006579.2) - SHH282805 from Creative biogene
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Human EBP siRNA - orb267787 from Biorbyt
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EBP shRNA Plasmid (Human) - CHH7285 from Cohesion Biosciences
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EBP miRNA 3'UTR clone - MiUTR3H-02637 from Creative biogene
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