| Gene Symbol |
FAAH2
|
| Entrez Gene |
158584
|
| Alt Symbol |
AMDD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
fatty acid amide hydrolase 2
|
| Other Description |
amidase domain containing|amidase domain-containing protein|anandamide amidohydrolase 2|fatty-acid amide hydrolase 2|oleamide hydrolase 2
|
| Swissprots |
Q86VT2 Q96N98 Q6GMR7
|
| Accessions |
EAW93245 Q6GMR7 AF086253 AK055766 BAB71007 BC048279 AAH48279 BC073922 AAH73922 BX110322 DA392815 EU285560 ABZ79724 HG512552 XM_005261982 XP_005262039 XM_005261984 XP_005262041 XM_005261985 XP_005262042 XM_005261986 XP_005262043 XM_005261987 XP_005262044 XM_011530767 XP_011529069 XR_938362 XR_938363 XR_938364 NM_174912 NP_777572
|
| Function |
Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. {ECO:0000269|PubMed:17015445}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in the brain, small intestine and testis. Also expressed in the heart, kidney, liver, lung and prostate. {ECO:0000269|PubMed:17015445}.
|