| Gene Symbol | IL7R |
|---|---|
| Entrez Gene | 3575 |
| Alt Symbol | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
| Species | Human |
| Gene Type | protein-coding |
| Description | interleukin 7 receptor |
| Other Description | CD127 antigen|IL-7 receptor subunit alpha|IL-7R subunit alpha|IL-7RA|interleukin 7 receptor alpha chain|interleukin 7 receptor isoform H5-6|interleukin-7 receptor subunit alpha |
| Swissprots | Q05CU8 Q6SV45 Q6NWM3 Q6NWM2 B4DVT1 P16871 Q6NSP4 Q9UPC1 B2RCS6 Q6NWM0 Q6NWM1 |
| Accessions | AAC83204 AAR08908 CAY55973 CCB84239 CCB84240 EAW55924 EAW55925 P16871 AA485865 AF373204 AK301220 BAG62793 AK315251 BAG37673 AL713738 BC020717 AAH20717 BC067537 AAH67537 BC067538 AAH67538 BC067539 AAH67539 BC067540 AAH67540 BC069999 AAH69999 CD703890 FJ529208 ACL80333 HQ447513 ADQ31999 M29696 AAA59157 XM_005248299 XP_005248356 XM_005248300 XP_005248357 XM_011514037 XP_011512339 NM_002185 NP_002176 NR_120485 |
| Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| Subcellular Location | Isoform 4: Secreted. |
| Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency, PI3K-Akt signaling pathway |