Gene Symbol | IL7R |
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Entrez Gene | 3575 |
Alt Symbol | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 7 receptor |
Other Description | CD127 antigen|IL-7 receptor subunit alpha|IL-7R subunit alpha|IL-7RA|interleukin 7 receptor alpha chain|interleukin 7 receptor isoform H5-6|interleukin-7 receptor subunit alpha |
Swissprots | Q05CU8 Q6SV45 Q6NWM3 Q6NWM2 B4DVT1 P16871 Q6NSP4 Q9UPC1 B2RCS6 Q6NWM0 Q6NWM1 |
Accessions | AAC83204 AAR08908 CAY55973 CCB84239 CCB84240 EAW55924 EAW55925 P16871 AA485865 AF373204 AK301220 BAG62793 AK315251 BAG37673 AL713738 BC020717 AAH20717 BC067537 AAH67537 BC067538 AAH67538 BC067539 AAH67539 BC067540 AAH67540 BC069999 AAH69999 CD703890 FJ529208 ACL80333 HQ447513 ADQ31999 M29696 AAA59157 XM_005248299 XP_005248356 XM_005248300 XP_005248357 XM_011514037 XP_011512339 NM_002185 NP_002176 NR_120485 |
Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
Subcellular Location | Isoform 4: Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency, PI3K-Akt signaling pathway |
IL-7R CRISPR/Cas9 KO Plasmid (h) - sc-401536 from Santa Cruz Biotechnology
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IL-7R HDR Plasmid (h) - sc-401536-HDR from Santa Cruz Biotechnology
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IL-7R Double Nickase Plasmid (h) - sc-401536-NIC from Santa Cruz Biotechnology
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IL-7R Double Nickase Plasmid (h2) - sc-401536-NIC-2 from Santa Cruz Biotechnology
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IL-7R CRISPR Activation Plasmid (h) - sc-401536-ACT from Santa Cruz Biotechnology
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IL-7R CRISPR Activation Plasmid (h2) - sc-401536-ACT-2 from Santa Cruz Biotechnology
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IL-7R Lentiviral Activation Particles (h) - sc-401536-LAC from Santa Cruz Biotechnology
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IL-7R Lentiviral Activation Particles (h2) - sc-401536-LAC-2 from Santa Cruz Biotechnology
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IL-7R siRNA (h) - sc-35664 from Santa Cruz Biotechnology
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IL-7R shRNA Plasmid (h) - sc-35664-SH from Santa Cruz Biotechnology
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IL-7R shRNA (h) Lentiviral Particles - sc-35664-V from Santa Cruz Biotechnology
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IL-7 R alpha/CD127 RNAi - H00003575-R02 from Novus Biologicals
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MISSION® esiRNA - EHU066561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10640 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10640 from Sigma-Aldrich
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IL7R siRNA (Human) - CRH2390 from Cohesion Biosciences
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IL7R - MBS8220985 from MyBioSource
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shRNA set against Human IL7R (NM_002185.3) - SHH319097 from Creative biogene
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Human IL7R siRNA - orb262892 from Biorbyt
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IL7R shRNA Plasmid (Human) - CHH2390 from Cohesion Biosciences
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IL7R miRNA 3'UTR clone - MiUTR3H-01138 from Creative biogene
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