Gene Symbol | QRSL1 |
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Entrez Gene | 55278 |
Alt Symbol | GatA |
Species | Human |
Gene Type | protein-coding |
Description | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 |
Other Description | glu-AdT subunit A|glutaminyl-tRNA synthase-like protein 1|glutamyl-tRNA(Gln) amidotransferase subunit A homolog|glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial|glutamyl-tRNA(Gln) amidotransferase, subunit A |
Swissprots | Q9HA60 Q9NV19 Q9H0R6 Q5VWJ4 |
Accessions | EAW48407 EAW48408 Q9H0R6 AK001851 BAA91941 AK022251 BAB13996 AK023509 BAB14592 AK225262 AK225443 AK314694 BAG37245 AL136679 CAB66614 BC006084 AAH06084 BC014389 AAH14389 DA819470 JF432225 ADZ15442 XM_011535924 XP_011534226 NM_018292 NP_060762 |
Function | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). {ECO:0000255|HAMAP-Rule:MF_03150, ECO:0000269|PubMed:19805282}. |
Subcellular Location | Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03150, ECO:0000269|PubMed:19805282}. |
Top Pathways | Aminoacyl-tRNA biosynthesis |
QRSL1 CRISPR/Cas9 KO Plasmid (h) - sc-412502 from Santa Cruz Biotechnology
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QRSL1 HDR Plasmid (h) - sc-412502-HDR from Santa Cruz Biotechnology
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QRSL1 Double Nickase Plasmid (h) - sc-412502-NIC from Santa Cruz Biotechnology
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QRSL1 Double Nickase Plasmid (h2) - sc-412502-NIC-2 from Santa Cruz Biotechnology
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QRSL1 CRISPR Activation Plasmid (h) - sc-412502-ACT from Santa Cruz Biotechnology
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QRSL1 CRISPR Activation Plasmid (h2) - sc-412502-ACT-2 from Santa Cruz Biotechnology
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QRSL1 Lentiviral Activation Particles (h) - sc-412502-LAC from Santa Cruz Biotechnology
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QRSL1 Lentiviral Activation Particles (h2) - sc-412502-LAC-2 from Santa Cruz Biotechnology
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QRSL1 siRNA (h) - sc-95120 from Santa Cruz Biotechnology
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QRSL1 shRNA Plasmid (h) - sc-95120-SH from Santa Cruz Biotechnology
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QRSL1 shRNA (h) Lentiviral Particles - sc-95120-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU105851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17791 from Sigma-Aldrich
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QRSL1 siRNA (Human) - CRJ0618 from Cohesion Biosciences
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QRSL1 - MBS8206383 from MyBioSource
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shRNA set against Human QRSL1 (NM_018292.4) - SHH387672 from Creative biogene
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Human QRSL1 siRNA - orb271119 from Biorbyt
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QRSL1 shRNA Plasmid (Human) - CHJ0618 from Cohesion Biosciences
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QRSL1 miRNA 3'UTR clone - MiUTR4H-TG07250 from Creative biogene
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