| Gene Symbol |
CIAO1
|
| Entrez Gene |
9391
|
| Alt Symbol |
CIA1, WDR39
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytosolic iron-sulfur assembly component 1
|
| Other Description |
WD repeat domain 39|WD repeat-containing protein 39|WD40 protein Ciao1|cytosolic iron-sulfur protein assembly 1 homolog|probable cytosolic iron-sulfur protein assembly protein CIAO1
|
| Swissprots |
Q53FM5 A0MNN9 O76071
|
| Accessions |
AAC23493 EAW71374 EAW71375 O76071 AF086118 AI094333 AK056423 AK092687 AK124703 AK223257 BAD96977 AK299503 BAG61458 AK315568 BAG37943 BC001395 AAH01395 BC032812 AAH32812 BE220199 BG108391 BI460314 CR456802 CAG33083 EF011618 ABK41108 EU176373 ABW03824 EU176710 ABW03511 U63810 AAC24948 NM_004804 NP_004795
|
| Function |
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. {ECO:0000255|HAMAP-Rule:MF_03037, ECO:0000269|PubMed:17937914, ECO:0000269|PubMed:20797633}.
|