BEX2

Gene Symbol BEX2
Entrez Gene 84707
Alt Symbol BEX1, DJ79P11.1
Species Human
Gene Type protein-coding
Description brain expressed X-linked 2
Other Description brain-expressed X-linked protein 2|hBex2|protein BEX2
Swissprots Q5JVV9 B2R574 D3DXA2 F5H7H5 Q9BXY8
Accessions CAD24039 EAW54715 EAW54716 Q9BXY8 AF251053 AAK34943 AK312085 BAG35021 AY833560 AAX40678 BC015522 AAH15522 BC050651 BI670202 BU569325 BU596902 CB961647 CD365521 CK001963 DB498563 NM_001168399 NP_001161871 NM_001168400 NP_001161872 NM_001168401 NP_001161873 NM_032621 NP_116010
Function Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. {ECO:0000269|PubMed:19711341}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:16314316}.
Tissue Specificity Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Widely expressed in breast cancer cell lines. {ECO:0000269|PubMed:15958283, ECO:0000269|PubMed:19711341}.

Bex2 CRISPR/Cas9 KO Plasmid (h) - sc-404711 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 HDR Plasmid (h) - sc-404711-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 Double Nickase Plasmid (h) - sc-404711-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 Double Nickase Plasmid (h2) - sc-404711-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 CRISPR Activation Plasmid (h) - sc-404711-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 CRISPR Activation Plasmid (h2) - sc-404711-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 Lentiviral Activation Particles (h) - sc-404711-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 Lentiviral Activation Particles (h2) - sc-404711-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bex2 siRNA (h) - sc-60271 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Bex2 shRNA Plasmid (h) - sc-60271-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Bex2 shRNA (h) Lentiviral Particles - sc-60271-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU111661 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3956 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3956 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02432 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02432

BEX2 siRNA (Human) - CRJ3596 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BEX2 - MBS8238952 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BEX2 (NM_032621.3) - SHH246450 from Creative biogene

Category siRNA
Species Reactivities Human

BEX2 shRNA Plasmid (Human) - CHJ3596 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BEX2 miRNA 3'UTR clone - MiUTR3H-02907 from Creative biogene

Species Reactivities Human
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