Gene Symbol |
ST8SIA2
|
Entrez Gene |
8128
|
Alt Symbol |
HsT19690, SIAT8B, ST8SIA-II, STX
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
|
Other Description |
SIAT8-B|ST8SiaII|alpha-2,8-sialyltransferase 8B|alpha-2,8-sialyltransferase 8B 1|sialyltransferase 8 (alpha-2, 8-sialytransferase) B|sialyltransferase 8B|sialyltransferase St8Sia II|sialyltransferase X|sialytransferase St8Sia II
|
Swissprots |
Q92470 Q92746 Q4VAZ0 Q92186
|
Accessions |
ACS13735 ACS13736 CAS91696 EAX02149 Q92186 AK313924 BAG36645 AW163487 AY358091 AAQ88458 BC069584 AAH69584 BC096202 AAH96202 BC096203 AAH96203 BC096204 AAH96204 BC096205 AAH96205 BX537981 L29556 AAA36613 U33551 AAC24458 U82762 AAB51242 NM_006011 NP_006002
|
Function |
May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
Tissue Specificity |
Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.
|