Gene Symbol | ADK |
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Entrez Gene | 132 |
Alt Symbol | AK |
Species | Human |
Gene Type | protein-coding |
Description | adenosine kinase |
Other Description | adenosine 5'-phosphotransferase |
Swissprots | O00742 Q16710 Q5JQ11 B7Z783 P55263 Q9BTN2 Q5JQ10 O00741 B7Z800 |
Accessions | AAG13958 EAW54555 EAW54556 P55263 AI188809 AI608983 AK290633 BAF83322 AK301590 BAH13519 AK302706 BAH13786 BC003568 AAH03568 BJ989861 BM472149 BT006788 AAP35434 CB133126 DA356691 DQ890624 ABM92241 EU176483 ABW03284 U33936 AAB01689 U50196 AAA97893 U90338 AAB50234 U90339 AAB50235 XM_011539297 XP_011537599 NM_001123 NP_001114 NM_001202449 NP_001189378 NM_001202450 NP_001189379 NM_006721 NP_006712 |
Function | ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides. |
Subcellular Location | Isoform 1: Nucleus. |
Tissue Specificity | Widely expressed. Highest level in placenta, liver, muscle and kidney. |
Top Pathways | Purine metabolism |
ADK CRISPR/Cas9 KO Plasmid (h) - sc-403273 from Santa Cruz Biotechnology
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ADK HDR Plasmid (h) - sc-403273-HDR from Santa Cruz Biotechnology
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ADK Double Nickase Plasmid (h) - sc-403273-NIC from Santa Cruz Biotechnology
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ADK Double Nickase Plasmid (h2) - sc-403273-NIC-2 from Santa Cruz Biotechnology
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ADK CRISPR Activation Plasmid (h) - sc-403273-ACT from Santa Cruz Biotechnology
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ADK CRISPR Activation Plasmid (h2) - sc-403273-ACT-2 from Santa Cruz Biotechnology
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ADK Lentiviral Activation Particles (h) - sc-403273-LAC from Santa Cruz Biotechnology
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ADK Lentiviral Activation Particles (h2) - sc-403273-LAC-2 from Santa Cruz Biotechnology
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ADK siRNA (h) - sc-38902 from Santa Cruz Biotechnology
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ADK shRNA Plasmid (h) - sc-38902-SH from Santa Cruz Biotechnology
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ADK shRNA (h) Lentiviral Particles - sc-38902-V from Santa Cruz Biotechnology
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ADK RNAi - H00000132-R06 from Novus Biologicals
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MISSION® esiRNA - EHU092681 from Sigma-Aldrich
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MISSION® siRNA - SIHK0063 from Sigma-Aldrich
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MISSION® siRNA - SIHK0061 from Sigma-Aldrich
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MISSION® siRNA - SIHK0062 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2885 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2885 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06897 from Sigma-Aldrich
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ADK siRNA (Human) - CRH0091 from Cohesion Biosciences
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ADK RNAi - H00000132-R05 from Novus Biologicals
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ADK - MBS8237215 from MyBioSource
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ADK HDR Plasmid (h2) - sc-403273-HDR-2 from Santa Cruz Biotechnology
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ADK CRISPR/Cas9 KO Plasmid (h2) - sc-403273-KO-2 from Santa Cruz Biotechnology
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shRNA set against Human ADK (NM_001123.3) - SHH232490 from Creative biogene
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