Gene Symbol | CD247 |
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Entrez Gene | 919 |
Alt Symbol | CD3-ZETA, CD3H, CD3Q, CD3Z, IMD25, T3Z, TCRZ |
Species | Human |
Gene Type | protein-coding |
Description | CD247 molecule |
Other Description | CD247 antigen, zeta subunit|CD3Z antigen, zeta polypeptide (TiT3 complex)|CD3zeta chain|T-cell antigen receptor complex, zeta subunit of CD3|T-cell receptor T3 zeta chain|T-cell surface glycoprotein CD3 zeta chain|TCR zeta chain |
Swissprots | B1AK49 Q8TAX4 Q5VX13 P20963 |
Accessions | A46461 AAB22030 AAB24602 AAY57330 EAW90790 EAW90791 EAW90792 P20963 AF228312 AAF34793 AI420774 AK128376 BAC87407 AK223325 BAD97045 AK313946 BAG36664 AL557555 BC025703 AAH25703 BI819937 DQ893778 ABM84704 EF079882 EF364117 EF364118 EF364119 ABQ28690 EU117371 ABW06577 EU117372 ABW06578 EU117373 ABW06579 EU118788 ABW96174 EU118789 ABW96175 EU118790 ABW96176 EU118791 ABW96177 EU118792 ABW96178 EU118793 ABW96179 EU176191 ABW03642 EU597245 ACC61185 J04132 AAA60394 X55510 X55511 X55512 XM_011510144 XP_011508446 XM_011510145 XP_011508447 NM_000734 NP_000725 NM_198053 NP_932170 |
Function | Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, Chagas disease (American trypanosomiasis) |
CD3-ζ siRNA (h) - sc-29245 from Santa Cruz Biotechnology
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CD3-ζ shRNA Plasmid (h) - sc-29245-SH from Santa Cruz Biotechnology
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CD3-ζ shRNA (h) Lentiviral Particles - sc-29245-V from Santa Cruz Biotechnology
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CD3 zeta RNAi - H00000919-R03 from Novus Biologicals
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MISSION® esiRNA - EHU159661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5704 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5704 from Sigma-Aldrich
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CD247 siRNA (Human) - CRH0647 from Cohesion Biosciences
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CD3 zeta RNAi - H00000919-R04 from Novus Biologicals
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CD247 - MBS8209224 from MyBioSource
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shRNA set against Human CD247 (NM_000734.3) - SHH258789 from Creative biogene
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shRNA set against Human CD247(NM_198053.2) - SHG156007 from Creative biogene
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CD247 shRNA Plasmid (Human) - CHH0647 from Cohesion Biosciences
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CD247 miRNA 3'UTR clone - MiUTR1H-01857 from Creative biogene
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CD247 miRNA 3'UTR clone - MiUTR1H-01858 from Creative biogene
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