| Gene Symbol |
HERC6
|
| Entrez Gene |
55008
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
| Other Description |
HECT domain and RCC1-like domain-containing protein 6|hect domain and RLD 6|potential ubiquitin ligase|probable E3 ubiquitin-protein ligase HERC6
|
| Swissprots |
Q5JPB6 Q8IVU3 Q9NWS4 B4DIY5 Q5HYM6 Q6PIF4 Q8NAN3 Q5GC90 Q5GRH3
|
| Accessions |
EAX06018 EAX06019 Q8IVU3 AF336798 AAQ14893 AK000644 BAA91303 AK092403 BAC03879 AK097168 BAG53428 AK225506 AK295832 BAG58647 AL832670 AL833664 CAI46151 AY653201 AAV66895 AY653202 AAV66896 AY653203 AAV66897 BC027846 BC035775 AAH35775 BC042047 AAH42047 BX647121 CAI46056 DA221524 DC344051 HG497065 XM_005263083 XP_005263140 XM_011532053 XP_011530355 XM_011532054 XP_011530356 XR_938752 NM_001013000 NM_001013002 NM_001013005 NM_001165136 NP_001158608 NM_017912 NP_060382
|
| Function |
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:15676274}.
|
| Tissue Specificity |
Detected in brain, heart, placenta and testis. {ECO:0000269|PubMed:15676274}.
|
![Western Blot: HERC6 Overexpression Lysate (Adult Normal) [NBP2-06902] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HERC6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8612_HERC6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06902-img0001.jpg)