MCCC1

Gene Symbol MCCC1
Entrez Gene 56922
Alt Symbol MCC-B, MCCA
Species Human
Gene Type protein-coding
Description methylcrotonoyl-CoA carboxylase 1 (alpha)
Other Description 3-methylcrotonyl-CoA carboxylase 1|3-methylcrotonyl-CoA carboxylase biotin-containing subunit|3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha|MCCase subunit alpha|methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial|methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Swissprots Q59ES4 Q9NS97 Q96RQ3 Q9H959
Accessions EAW78339 EAW78340 Q96RQ3 AB029826 BAA99407 AB209737 BAD92974 AF297332 AAK67986 AF310339 AAG50245 AF310972 AAG53095 AK023051 BAB14377 AK098411 AK294882 BAG57977 AK295293 BAG58277 AK316428 BAH14799 AL442091 AL532496 AL556872 BC004187 AAH04187 BC004214 AAH04214 BC036395 BC042453 BF795651 CR749608 CAH18403 DA487016 XM_006713702 XP_006713765 XM_011512992 XP_011511294 XM_011512993 XP_011511295 XR_241502 XR_924159 NM_001293273 NP_001280202 NM_020166 NP_064551 NR_120639 NR_120640
Function Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. {ECO:0000269|PubMed:17360195}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:16023992}.
Top Pathways Valine, leucine and isoleucine degradation

MCCA CRISPR/Cas9 KO Plasmid (h) - sc-410600 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA HDR Plasmid (h) - sc-410600-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA Double Nickase Plasmid (h) - sc-410600-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA Double Nickase Plasmid (h2) - sc-410600-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA CRISPR Activation Plasmid (h) - sc-410600-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA CRISPR Activation Plasmid (h2) - sc-410600-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA Lentiviral Activation Particles (h) - sc-410600-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA Lentiviral Activation Particles (h2) - sc-410600-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCCA siRNA (h) - sc-45692 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCCA shRNA Plasmid (h) - sc-45692-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCCA shRNA (h) Lentiviral Particles - sc-45692-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU004291 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13105 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13105 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01146 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01146

MCCC1 siRNA (Human) - CRJ1225 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MCCC1 RNAi - H00056922-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MCCC1 (NM_020166.3) - SHH339155 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MCCC1(NM_020166.3) - SHH180749 from Creative biogene

Category siRNA
Species Reactivities Human

Human MCCC1 siRNA - orb271726 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MCCC1 shRNA Plasmid (Human) - CHJ1225 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCCC1 miRNA 3'UTR clone - MiUTR1H-06158 from Creative biogene

Species Reactivities Human
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