SLC22A18

Gene Symbol SLC22A18
Entrez Gene 5002
Alt Symbol BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A
Species Human
Gene Type protein-coding
Description solute carrier family 22, member 18
Other Description Beckwith-Wiedemann syndrome chromosome region 1, candidate A|ORCTL-2|beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein|efflux transporter-like protein|imprinted multi-membrane spanning polyspecific transporter-related protein 1|imprinted multi-membrane-spanning polyspecific transporter-related protein 1|organic cation transporter-like 2|organic cation transporter-like protein 2|p45 Beckwith-Wiedemann region 1A|p45-Beckwith-Wiedemann region 1 A|solute carrier family 22 member 18|tumor-suppressing STF cDNA 5 protein|tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein
Swissprots Q7LGF7 Q96BI1 O14906 O60680 Q7LDS5 O43562 O60485
Accessions EAX02528 EAX02529 EAX02530 Q96BI1 AB012083 BAA32779 AF028738 AAB82727 AF030302 AAC17492 AF037064 AAC04787 AF059663 AAC14725 AF070479 AAC23505 AL832892 CAH10416 AW452749 BC015571 AAH15571 BG489795 BG684685 BM561526 BP350681 DA582280 EU176788 ABW03589 XM_005252952 XP_005253009 XM_005252953 XP_005253010 XM_006718243 XP_006718306 XM_006725127 XP_006725190 XM_006725128 XP_006725191 XM_011520140 XP_011518442 XM_011520141 XP_011518443 XM_011520142 XP_011518444 XM_011520143 XP_011518445 XM_011546585 XP_011544887 XM_011546586 XP_011544888 XM_011546587 XP_011544889 XM_011546588 XP_011544890 XM_011546589 XP_011544891 XM_011546590 XP_011544892 NM_002555 NP_002546 NM_183233 NP_899056
Function May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney. {ECO:0000269|PubMed:9744804}.
Subcellular Location Apical cell membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Note=Localized at the apical membrane surface of renal proximal tubules. {ECO:0000269|PubMed:9744804}.
Tissue Specificity Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung. {ECO:0000269|PubMed:9499412, ECO:0000269|PubMed:9520460, ECO:0000269|PubMed:9570947, ECO:0000269|PubMed:9744804}.

ORCTL2 CRISPR/Cas9 KO Plasmid (h) - sc-407573 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 HDR Plasmid (h) - sc-407573-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 Double Nickase Plasmid (h) - sc-407573-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 Double Nickase Plasmid (h2) - sc-407573-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 CRISPR Activation Plasmid (h) - sc-407573-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 CRISPR Activation Plasmid (h2) - sc-407573-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 Lentiviral Activation Particles (h) - sc-407573-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 Lentiviral Activation Particles (h2) - sc-407573-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORCTL2 siRNA (h) - sc-96398 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ORCTL2 shRNA Plasmid (h) - sc-96398-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ORCTL2 shRNA (h) Lentiviral Particles - sc-96398-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Solute carrier family 22 member 18 RNAi - H00005002-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Solute carrier family 22 member 18 RNAi - H00005002-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU063031 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2570 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

SLC22A18 siRNA (Human) - CRH3320 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC22A18 - MBS8218471 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC22A18 (NM_183233.2) - SHH409096 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC22A18 siRNA - orb263822 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC22A18 shRNA Plasmid (Human) - CHH3320 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC22A18 miRNA 3'UTR clone - MiUTR3H-05153 from Creative biogene

Species Reactivities Human

SLC22A18 miRNA 3'UTR clone - MiUTR3H-05154 from Creative biogene

Species Reactivities Human
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