| Gene Symbol | Dao |
|---|---|
| Entrez Gene | 13142 |
| Alt Symbol | AI987963, DAAO, DAMOX, Dao-1, Dao1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | D-amino acid oxidase |
| Other Description | D-amino acid oxidase 1|D-amino-acid oxidase |
| Swissprots | Q64465 P18894 Q8VCW7 |
| Accessions | EDL19928 EDL19929 EDL19930 P18894 AI530495 AK134813 BAE22296 AW492600 BB843516 BC015269 AAH15269 BC018377 AAH18377 BE651085 BU755879 D10210 BAA01062 D10211 BAA01063 M32299 AAA39367 XM_006530161 XP_006530224 XM_006530162 XP_006530225 NM_001286396 NP_001273325 NM_001286397 NP_001273326 NM_010018 NP_034148 |
| Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. |
| Subcellular Location | Peroxisome. |
| Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |