Gene Symbol | Dao |
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Entrez Gene | 13142 |
Alt Symbol | AI987963, DAAO, DAMOX, Dao-1, Dao1 |
Species | Mouse |
Gene Type | protein-coding |
Description | D-amino acid oxidase |
Other Description | D-amino acid oxidase 1|D-amino-acid oxidase |
Swissprots | Q64465 P18894 Q8VCW7 |
Accessions | EDL19928 EDL19929 EDL19930 P18894 AI530495 AK134813 BAE22296 AW492600 BB843516 BC015269 AAH15269 BC018377 AAH18377 BE651085 BU755879 D10210 BAA01062 D10211 BAA01063 M32299 AAA39367 XM_006530161 XP_006530224 XM_006530162 XP_006530225 NM_001286396 NP_001273325 NM_001286397 NP_001273326 NM_010018 NP_034148 |
Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. |
Subcellular Location | Peroxisome. |
Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |
DAAO CRISPR/Cas9 KO Plasmid (m) - sc-419943 from Santa Cruz Biotechnology
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DAAO HDR Plasmid (m) - sc-419943-HDR from Santa Cruz Biotechnology
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DAAO Double Nickase Plasmid (m) - sc-419943-NIC from Santa Cruz Biotechnology
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DAAO Double Nickase Plasmid (m2) - sc-419943-NIC-2 from Santa Cruz Biotechnology
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DAAO CRISPR Activation Plasmid (m) - sc-419943-ACT from Santa Cruz Biotechnology
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DAAO CRISPR Activation Plasmid (m2) - sc-419943-ACT-2 from Santa Cruz Biotechnology
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DAAO Lentiviral Activation Particles (m) - sc-419943-LAC from Santa Cruz Biotechnology
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DAAO Lentiviral Activation Particles (m2) - sc-419943-LAC-2 from Santa Cruz Biotechnology
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DAAO siRNA (m) - sc-142864 from Santa Cruz Biotechnology
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DAAO shRNA Plasmid (m) - sc-142864-SH from Santa Cruz Biotechnology
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DAAO shRNA (m) Lentiviral Particles - sc-142864-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN29698 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29698 from Sigma-Aldrich
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DAO siRNA (Mouse) - CRM0969 from Cohesion Biosciences
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DAO - MBS8223573 from MyBioSource
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shRNA set against Mouse DAO (NM_010018.2) - SHH274497 from Creative biogene
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shRNA set against Mouse Dao1(NM_010018.2) - SHG221317 from Creative biogene
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Mouse DAO siRNA - orb280445 from Biorbyt
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DAO shRNA Plasmid (Mouse) - CHM0969 from Cohesion Biosciences
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DAO miRNA 3'UTR clone - MiUTR1M-03688 from Creative biogene
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