CSH2
| Gene Symbol | CSH2 |
|---|---|
| Entrez Gene | 1443 |
| Alt Symbol | CS-2, CSB, PL, hCS-B |
| Species | Human |
| Gene Type | protein-coding |
| Description | chorionic somatomammotropin hormone 2 |
| Other Description | choriomammotropin|chorionic somatomammotropin B|lactogen|placental lactogen |
| Swissprots | P0DML3 |
| Accessions | AAA52116 AAA52553 AAA98747 ABZ88723 ABZ88724 ABZ88725 P0DML3 BC022044 AAH22044 BC035965 AAH35965 BC119748 AAI19749 CR615915 DQ892826 ABM83752 DQ896072 ABM87071 V00573 CAA23836 NM_020991 NP_066271 NM_022644 NP_072170 NM_022645 NP_072171 |
| Function | Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. {ECO:0000269|PubMed:16546209}. |
| Subcellular Location | Secreted. |
| Top Pathways | Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction |
Placental lactogen II CRISPR/Cas9 KO Plasmid (h) - sc-402301 from Santa Cruz Biotechnology
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Placental lactogen II HDR Plasmid (h) - sc-402301-HDR from Santa Cruz Biotechnology
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Placental lactogen II Double Nickase Plasmid (h) - sc-402301-NIC from Santa Cruz Biotechnology
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Placental lactogen II Double Nickase Plasmid (h2) - sc-402301-NIC-2 from Santa Cruz Biotechnology
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Placental lactogen II CRISPR Activation Plasmid (h) - sc-402301-ACT from Santa Cruz Biotechnology
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Placental lactogen II CRISPR Activation Plasmid (h2) - sc-402301-ACT-2 from Santa Cruz Biotechnology
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Placental lactogen II Lentiviral Activation Particles (h) - sc-402301-LAC from Santa Cruz Biotechnology
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Placental lactogen II Lentiviral Activation Particles (h2) - sc-402301-LAC-2 from Santa Cruz Biotechnology
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Placental lactogen II siRNA (h) - sc-39515 from Santa Cruz Biotechnology
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Lactogen shRNA Plasmid (h) - sc-39515-SH from Santa Cruz Biotechnology
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Lactogen shRNA (h) Lentiviral Particles - sc-39515-V from Santa Cruz Biotechnology
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CSH2 RNAi - H00001443-R01 from Novus Biologicals
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CSH2 RNAi - H00001443-R03 from Novus Biologicals
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CSH2 RNAi - H00001443-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN6636 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6636 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04822 from Sigma-Aldrich
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CSH2 siRNA (Human) - CRH1017 from Cohesion Biosciences
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shRNA set against Human CSH2 (NM_020991.3) - SHH270329 from Creative biogene
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shRNA set against Human CSH2(NM_022645.2) - SHG202897 from Creative biogene
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shRNA set against Human CSH2(NM_020991.3) - SHG202948 from Creative biogene
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CSH2 shRNA Plasmid (Human) - CHH1017 from Cohesion Biosciences
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CSH2 miRNA 3'UTR clone - MiUTR1H-02462 from Creative biogene
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CSH2 miRNA 3'UTR clone - MiUTR1H-02463 from Creative biogene
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CSH2 miRNA 3'UTR clone - MiUTR3H-00448 from Creative biogene
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