Gene Symbol | SKIV2L2 |
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Entrez Gene | 23517 |
Alt Symbol | Dob1, KIAA0052, Mtr4, fSAP118 |
Species | Human |
Gene Type | protein-coding |
Description | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
Other Description | ATP-dependent RNA helicase SKIV2L2|ATP-dependent helicase SKIV2L2|TRAMP-like complex helicase|functional spliceosome-associated protein 118|superkiller viralicidic activity 2-like 2 |
Swissprots | Q8N5R0 Q6MZZ8 Q2M386 Q8TAG2 Q6P170 P42285 |
Accessions | CCQ43506 EAW54919 P42285 AK123505 AK291649 BAF84338 AK304788 BAG65538 BC014669 AAH14669 BC028604 AAH28604 BC031779 AAH31779 BC065258 AAH65258 BC104996 AAI04997 BC105291 AAI05292 BC113509 AAI13510 BX640789 CAE45877 D29641 BAA06124 DA524147 NM_015360 NP_056175 |
Function | May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. {ECO:0000269|PubMed:17412707}. |
Subcellular Location | Nucleus, nucleoplasm. Nucleus, nucleolus. |
Top Pathways | RNA degradation |
SKIV2L2 CRISPR/Cas9 KO Plasmid (h) - sc-411757 from Santa Cruz Biotechnology
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SKIV2L2 HDR Plasmid (h) - sc-411757-HDR from Santa Cruz Biotechnology
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SKIV2L2 Double Nickase Plasmid (h) - sc-411757-NIC from Santa Cruz Biotechnology
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SKIV2L2 Double Nickase Plasmid (h2) - sc-411757-NIC-2 from Santa Cruz Biotechnology
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SKIV2L2 CRISPR Activation Plasmid (h) - sc-411757-ACT from Santa Cruz Biotechnology
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SKIV2L2 CRISPR Activation Plasmid (h2) - sc-411757-ACT-2 from Santa Cruz Biotechnology
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SKIV2L2 Lentiviral Activation Particles (h) - sc-411757-LAC from Santa Cruz Biotechnology
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SKIV2L2 Lentiviral Activation Particles (h2) - sc-411757-LAC-2 from Santa Cruz Biotechnology
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SKIV2L2 siRNA (h) - sc-91681 from Santa Cruz Biotechnology
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SKIV2L2 shRNA Plasmid (h) - sc-91681-SH from Santa Cruz Biotechnology
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SKIV2L2 shRNA (h) Lentiviral Particles - sc-91681-V from Santa Cruz Biotechnology
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SKIV2L2 RNAi - H00023517-R01 from Novus Biologicals
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MISSION® esiRNA - EHU010001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19382 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19382 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00517 from Sigma-Aldrich
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SKIV2L2 siRNA (Human) - CRH8323 from Cohesion Biosciences
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SKIV2L2 - MBS8200951 from MyBioSource
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shRNA set against Human SKIV2L2 (NM_015360.4) - SHH408040 from Creative biogene
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Human SKIV2L2 siRNA - orb268825 from Biorbyt
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SKIV2L2 shRNA Plasmid (Human) - CHH8323 from Cohesion Biosciences
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SKIV2L2 miRNA 3'UTR clone - MiUTR3H-16074 from Creative biogene
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