Gene Symbol | MMD |
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Entrez Gene | 23531 |
Alt Symbol | MMA, MMD1, PAQR11 |
Species | Human |
Gene Type | protein-coding |
Description | monocyte to macrophage differentiation-associated |
Other Description | macrophage maturation-associated|monocyte to macrophage differentiation factor|monocyte to macrophage differentiation protein|progestin and adipoQ receptor family member 11|progestin and adipoQ receptor family member XI |
Swissprots | Q15546 D3DTY6 B2R6X9 Q8TAN7 |
Accessions | CBS99541 EAW94541 EAW94542 Q15546 AK303810 BAG64763 AK312760 BAG35626 AY424289 AAR08377 BC026324 AAH26324 BI546449 CR541893 CAG46691 DQ892362 ABM83288 DQ895569 ABM86495 N40480 X85750 CAA59752 XM_006721795 XP_006721858 XR_429880 XR_934430 NM_012329 NP_036461 |
Function | Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion. {ECO:0000250}. |
Subcellular Location | Late endosome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Exhibits relatively ubiquitous expression with preferential expression in mature (in vitro differentiated) macrophages. {ECO:0000269|PubMed:16044242}. |
MMD CRISPR/Cas9 KO Plasmid (h) - sc-409243 from Santa Cruz Biotechnology
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MMD HDR Plasmid (h) - sc-409243-HDR from Santa Cruz Biotechnology
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MMD Double Nickase Plasmid (h) - sc-409243-NIC from Santa Cruz Biotechnology
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MMD Double Nickase Plasmid (h2) - sc-409243-NIC-2 from Santa Cruz Biotechnology
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MMD CRISPR Activation Plasmid (h) - sc-409243-ACT from Santa Cruz Biotechnology
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MMD CRISPR Activation Plasmid (h2) - sc-409243-ACT-2 from Santa Cruz Biotechnology
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MMD Lentiviral Activation Particles (h) - sc-409243-LAC from Santa Cruz Biotechnology
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MMD Lentiviral Activation Particles (h2) - sc-409243-LAC-2 from Santa Cruz Biotechnology
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MMD siRNA (h) - sc-93685 from Santa Cruz Biotechnology
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MMD shRNA Plasmid (h) - sc-93685-SH from Santa Cruz Biotechnology
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MMD shRNA (h) Lentiviral Particles - sc-93685-V from Santa Cruz Biotechnology
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MMD RNAi - H00023531-R02 from Novus Biologicals
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MISSION® esiRNA - EHU013721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14419 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14419 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10180 from Sigma-Aldrich
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MMD siRNA (Human) - CRH8336 from Cohesion Biosciences
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shRNA set against Human MMD (NM_012329.2) - SHH342784 from Creative biogene
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shRNA set against Human MMD(NM_012329.2) - SHH193061 from Creative biogene
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MMD shRNA Plasmid (Human) - CHH8336 from Cohesion Biosciences
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MMD miRNA 3'UTR clone - MiUTR1H-06343 from Creative biogene
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